Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash

S. F. Kingsmore, O. E. Silva, B. D. Hall, E. A. Sheldon, L. D. Cripe, E. W. St. Clair

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Multicentric Castleman's disease (MCD), or multicentric angiofollicular lymph node hyperplasia, is an uncommon lymphoproliferative disorder which typically presents with constitutional symptoms, multicentric lymphadenopathy, hepatosplenomegaly, effusions, and ascites. We describe a patient with several novel manifestations of MCD: sicca syndrome, lacrimal and salivary gland enlargement, cardiomyopathy, and palmar and plantar rash. Treatment of MCD with chlorambucil and prednisone was effective in the short term followup of this patient. MCD merits consideration in patients with lymphadenopathy and multisystem disease, including sicca syndrome, heart failure or rash.

Original languageEnglish
Pages (from-to)1588-1591
Number of pages4
JournalJournal of Rheumatology
Volume20
Issue number9
StatePublished - Dec 1 1993

Fingerprint

Sjogren's Syndrome
Exanthema
Cardiomyopathies
Giant Lymph Node Hyperplasia
Chlorambucil
Lacrimal Apparatus
Lymphoproliferative Disorders
Prednisone
Salivary Glands
Ascites
Heart Failure
Multi-centric Castleman's Disease
Lymphadenopathy
Therapeutics

Keywords

  • CARDIOMYOPATHY
  • LYMPHADENOPATHY
  • MULTICENTRIC CASTLEMAN'S DISEASE
  • SICCA SYNDROME

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Kingsmore, S. F., Silva, O. E., Hall, B. D., Sheldon, E. A., Cripe, L. D., & St. Clair, E. W. (1993). Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. Journal of Rheumatology, 20(9), 1588-1591.

Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. / Kingsmore, S. F.; Silva, O. E.; Hall, B. D.; Sheldon, E. A.; Cripe, L. D.; St. Clair, E. W.

In: Journal of Rheumatology, Vol. 20, No. 9, 01.12.1993, p. 1588-1591.

Research output: Contribution to journalArticle

Kingsmore, SF, Silva, OE, Hall, BD, Sheldon, EA, Cripe, LD & St. Clair, EW 1993, 'Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash', Journal of Rheumatology, vol. 20, no. 9, pp. 1588-1591.
Kingsmore SF, Silva OE, Hall BD, Sheldon EA, Cripe LD, St. Clair EW. Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. Journal of Rheumatology. 1993 Dec 1;20(9):1588-1591.
Kingsmore, S. F. ; Silva, O. E. ; Hall, B. D. ; Sheldon, E. A. ; Cripe, L. D. ; St. Clair, E. W. / Presentation of multicentric Castleman's disease with sicca syndrome, cardiomyopathy, palmar and plantar rash. In: Journal of Rheumatology. 1993 ; Vol. 20, No. 9. pp. 1588-1591.
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