Background: We sought to examine whether preoperative endoscopic retrograde cholangio-pancreatography (ERCP) increases the risk of surgical site infections (SSI) after laparoscopic cholecystectomy. Methods: Patients admitted to an academic hospital from 2010 to 2016, who were older than 18 and had a laparoscopic or a laparoscopic converted to open cholecystectomy for complicated biliary tract disease were included. We compared those who had a preoperative ERCP to those who did not. Our primary endpoint was the rate of SSI. Results: A total of 640 patients were included. Of them, 122 (19.1%) received preoperative ERCP and 518 (80.9%) did not. The former had different preoperative diagnoses compared to non-ERCP patients (choledocholithiasis [35.2%–7.0%], acute cholecystitis [31.2%–76.4%], gallstone pancreatitis [20.5%–16.2%], and cholangitis [13.1%–0.4%], p < 0.001). The rate of SSI was higher in the preoperative ERCP group (11.5%–4.0%, p = 0.005). In a multivariable analysis conversion to open (OR = 2.57, 95% CI = 1.06–6.21, p = 0.037) and preoperative ERCP (OR = 3.12, 95% CI = 1.34–7.22, p = 0.008) were the only independent predictors of SSI. Conclusion: Preoperative ERCP is associated with a threefold increase in the risk of SSI after laparoscopic cholecystectomy.
- Endoscopic retrograde cholangio-pancreatography
- Laparoscopic cholecystectomy
- Surgical site infection
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