Prenatal diagnosis and therapy for a fetal hepatic vascular malformation

A. A. Mejides, A. M. Adra, M. Adra, M. J. O'Sullivan, M. C. Nicholas

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: Congenital hepatic arteriovenous malformations complicated by high-output heart failure and hematologic derangements are associated with up to 90% mortality. Prenatal diagnosis alerts the pediatrician to the need for early neonatal intervention. Case: A fetal hepatic arteriovenous malformation with associated high-output cardiac failure was diagnosed at 29 weeks' gestation using real-time and color now Doppler sonography. Hydrocortisone injected directly into the umbilical vein and the amniotic sac resulted in appreciable improvement in hemodynamic and hematologic indices. The pregnancy ended in a preterm delivery at 31 weeks with no evidence of heart failure at birth. Conclusion: The compromised preterm fetus with a hepatic arteriovenous malformation can be treated in utero, avoiding early emergency delivery.

Original languageEnglish
Pages (from-to)850-853
Number of pages4
JournalObstetrics and Gynecology
Volume85
Issue number5 II SUPPL.
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

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Fetal Therapies
Vascular Malformations
Arteriovenous Malformations
Prenatal Diagnosis
Heart Failure
Liver
Doppler Color Ultrasonography
Pregnancy
Umbilical Veins
Hydrocortisone
Fetus
Emergencies
Hemodynamics
Parturition
Mortality

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Mejides, A. A., Adra, A. M., Adra, M., O'Sullivan, M. J., & Nicholas, M. C. (1995). Prenatal diagnosis and therapy for a fetal hepatic vascular malformation. Obstetrics and Gynecology, 85(5 II SUPPL.), 850-853. https://doi.org/10.1016/0029-7844(94)00227-5

Prenatal diagnosis and therapy for a fetal hepatic vascular malformation. / Mejides, A. A.; Adra, A. M.; Adra, M.; O'Sullivan, M. J.; Nicholas, M. C.

In: Obstetrics and Gynecology, Vol. 85, No. 5 II SUPPL., 01.01.1995, p. 850-853.

Research output: Contribution to journalArticle

Mejides, AA, Adra, AM, Adra, M, O'Sullivan, MJ & Nicholas, MC 1995, 'Prenatal diagnosis and therapy for a fetal hepatic vascular malformation', Obstetrics and Gynecology, vol. 85, no. 5 II SUPPL., pp. 850-853. https://doi.org/10.1016/0029-7844(94)00227-5
Mejides AA, Adra AM, Adra M, O'Sullivan MJ, Nicholas MC. Prenatal diagnosis and therapy for a fetal hepatic vascular malformation. Obstetrics and Gynecology. 1995 Jan 1;85(5 II SUPPL.):850-853. https://doi.org/10.1016/0029-7844(94)00227-5
Mejides, A. A. ; Adra, A. M. ; Adra, M. ; O'Sullivan, M. J. ; Nicholas, M. C. / Prenatal diagnosis and therapy for a fetal hepatic vascular malformation. In: Obstetrics and Gynecology. 1995 ; Vol. 85, No. 5 II SUPPL. pp. 850-853.
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