Prenatal diagnosis and therapy for a fetal hepatic vascular malformation

A. A. Mejides, A. M. Adra, M. Adra, M. J. O'Sullivan, M. C. Nicholas

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Background: Congenital hepatic arteriovenous malformations complicated by high-output heart failure and hematologic derangements are associated with up to 90% mortality. Prenatal diagnosis alerts the pediatrician to the need for early neonatal intervention. Case: A fetal hepatic arteriovenous malformation with associated high-output cardiac failure was diagnosed at 29 weeks' gestation using real-time and color now Doppler sonography. Hydrocortisone injected directly into the umbilical vein and the amniotic sac resulted in appreciable improvement in hemodynamic and hematologic indices. The pregnancy ended in a preterm delivery at 31 weeks with no evidence of heart failure at birth. Conclusion: The compromised preterm fetus with a hepatic arteriovenous malformation can be treated in utero, avoiding early emergency delivery.

Original languageEnglish
Pages (from-to)850-853
Number of pages4
JournalObstetrics and Gynecology
Volume85
Issue number5 II SUPPL.
DOIs
StatePublished - Jan 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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    Mejides, A. A., Adra, A. M., Adra, M., O'Sullivan, M. J., & Nicholas, M. C. (1995). Prenatal diagnosis and therapy for a fetal hepatic vascular malformation. Obstetrics and Gynecology, 85(5 II SUPPL.), 850-853. https://doi.org/10.1016/0029-7844(94)00227-5