Prenatal depression effects on neonates

Brenda L. Lundy, Nancy Aaron Jones, Tiffany M Field, Graciela Nearing, Marisabel Davalos, Paul A. Pietro, Saul Schanberg, Cynthia Kuhn

Research output: Contribution to journalArticle

265 Citations (Scopus)

Abstract

Sixty-three pregnant women (36 with depression symptoms) were recruited during their last trimester of pregnancy. The depressed mothers had higher cortisol and norepinephrine levels and lower dopamine levels. Their infants subsequently had higher cortisol and norepinephrine levels and lower dopamine levels at the neonatal stage. The neonates of depressed mothers also showed inferior performance on the orientation, reflex, excitability, and withdrawal clusters of the Brazelton Neonatal Behavioral Assessment. Stepwise regression analyses revealed that the depressed mothers' prenatal norepinephrine and dopamine levels significantly predicted the newborns' norepinephrine and dopamine levels and their Brazelton scores, highlighting an early biochemical influence on neonatal outcome.

Original languageEnglish
Pages (from-to)119-129
Number of pages11
JournalInfant Behavior and Development
Volume22
Issue number1
DOIs
StatePublished - Dec 1 1999
Externally publishedYes

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Dopamine
Norepinephrine
Newborn Infant
Depression
Mothers
Hydrocortisone
Third Pregnancy Trimester
Reflex
Pregnant Women
Regression Analysis
Pregnancy

Keywords

  • Biochemical correlates
  • Maternal depression
  • Prenatal depression

ASJC Scopus subject areas

  • Developmental and Educational Psychology

Cite this

Lundy, B. L., Jones, N. A., Field, T. M., Nearing, G., Davalos, M., Pietro, P. A., ... Kuhn, C. (1999). Prenatal depression effects on neonates. Infant Behavior and Development, 22(1), 119-129. https://doi.org/10.1016/S0163-6383(99)80009-5

Prenatal depression effects on neonates. / Lundy, Brenda L.; Jones, Nancy Aaron; Field, Tiffany M; Nearing, Graciela; Davalos, Marisabel; Pietro, Paul A.; Schanberg, Saul; Kuhn, Cynthia.

In: Infant Behavior and Development, Vol. 22, No. 1, 01.12.1999, p. 119-129.

Research output: Contribution to journalArticle

Lundy, BL, Jones, NA, Field, TM, Nearing, G, Davalos, M, Pietro, PA, Schanberg, S & Kuhn, C 1999, 'Prenatal depression effects on neonates', Infant Behavior and Development, vol. 22, no. 1, pp. 119-129. https://doi.org/10.1016/S0163-6383(99)80009-5
Lundy BL, Jones NA, Field TM, Nearing G, Davalos M, Pietro PA et al. Prenatal depression effects on neonates. Infant Behavior and Development. 1999 Dec 1;22(1):119-129. https://doi.org/10.1016/S0163-6383(99)80009-5
Lundy, Brenda L. ; Jones, Nancy Aaron ; Field, Tiffany M ; Nearing, Graciela ; Davalos, Marisabel ; Pietro, Paul A. ; Schanberg, Saul ; Kuhn, Cynthia. / Prenatal depression effects on neonates. In: Infant Behavior and Development. 1999 ; Vol. 22, No. 1. pp. 119-129.
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