Prenatal cocaine exposure: Cardiorespiratory function and resilience

Stephen J. Sheinkopf, Linda L. Lagasse, Barry M. Lester, Jing Liu, Ronald Seifer, Charles R. Bauer, Seetha Shankaran, Henrietta Bada, Rosemary Higgins, Abhik Das

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Cardiac vagal tone (VT) was studied as a resilience factor in children prenatally exposed to cocaine and nonexposed controls (n = 550). A cumulative risk index was derived and used to classify children as high versus low risk. VT was measured during mildly stressful observations at 1 and 36 months of age. Children were classified as having consistently high, consistently low, or fluctuating VT. Risk and VT interacted to predict adaptive behaviors. For high-risk children, low VT was related to higher ratings of adaptive behaviors. This finding suggests that regulatory functioning, as indexed by VT, may be a protective factor in prenatal CE.

Original languageEnglish (US)
Title of host publicationResilience in Children
PublisherBlackwell Publishing Inc.
Pages354-358
Number of pages5
ISBN (Print)1573316431, 9781573316439
DOIs
StatePublished - Dec 2006

Publication series

NameAnnals of the New York Academy of Sciences
Volume1094
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Children
  • Cocaine
  • Cumulative risk
  • Developmental outcome
  • Heart rate variability
  • Prenatal drug exposure
  • Vagal tone

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Sheinkopf, S. J., Lagasse, L. L., Lester, B. M., Liu, J., Seifer, R., Bauer, C. R., Shankaran, S., Bada, H., Higgins, R., & Das, A. (2006). Prenatal cocaine exposure: Cardiorespiratory function and resilience. In Resilience in Children (pp. 354-358). (Annals of the New York Academy of Sciences; Vol. 1094). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1376.049