Prenatal cocaine exposure: Cardiorespiratory function and resilience

Stephen J. Sheinkopf; Linda L. Lagasse; Barry M. Lester; Jing Liu; Ronald Seifer; Charles R. Bauer; Seetha Shankaran; Henrietta Bada; Rosemary Higgins; Abhik Das

doi:10.1196/annals.1376.049

Prenatal cocaine exposure: Cardiorespiratory function and resilience

Stephen J. Sheinkopf, Linda L. Lagasse, Barry M. Lester, Jing Liu, Ronald Seifer, Charles R. Bauer, Seetha Shankaran, Henrietta Bada, Rosemary Higgins, Abhik Das

Pediatrics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Cardiac vagal tone (VT) was studied as a resilience factor in children prenatally exposed to cocaine and nonexposed controls (n = 550). A cumulative risk index was derived and used to classify children as high versus low risk. VT was measured during mildly stressful observations at 1 and 36 months of age. Children were classified as having consistently high, consistently low, or fluctuating VT. Risk and VT interacted to predict adaptive behaviors. For high-risk children, low VT was related to higher ratings of adaptive behaviors. This finding suggests that regulatory functioning, as indexed by VT, may be a protective factor in prenatal CE.

Original language	English (US)
Title of host publication	Resilience in Children
Publisher	Blackwell Publishing Inc.
Pages	354-358
Number of pages	5
ISBN (Print)	1573316431, 9781573316439
DOIs	https://doi.org/10.1196/annals.1376.049
State	Published - Dec 2006

Publication series

Name	Annals of the New York Academy of Sciences
Volume	1094
ISSN (Print)	0077-8923
ISSN (Electronic)	1749-6632

Keywords

Children
Cocaine
Cumulative risk
Developmental outcome
Heart rate variability
Prenatal drug exposure
Vagal tone

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Access to Document

10.1196/annals.1376.049

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Sheinkopf, S. J., Lagasse, L. L., Lester, B. M., Liu, J., Seifer, R., Bauer, C. R., Shankaran, S., Bada, H., Higgins, R., & Das, A. (2006). Prenatal cocaine exposure: Cardiorespiratory function and resilience. In Resilience in Children (pp. 354-358). (Annals of the New York Academy of Sciences; Vol. 1094). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1376.049

Prenatal cocaine exposure : Cardiorespiratory function and resilience. / Sheinkopf, Stephen J.; Lagasse, Linda L.; Lester, Barry M.; Liu, Jing; Seifer, Ronald; Bauer, Charles R.; Shankaran, Seetha; Bada, Henrietta; Higgins, Rosemary; Das, Abhik.

Resilience in Children. Blackwell Publishing Inc., 2006. p. 354-358 (Annals of the New York Academy of Sciences; Vol. 1094).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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