Abstract
We investigated the value of prekeratin immunostaining in establishing the diagnosis of undifferentiated carcinoma of the nasopharyngeal type (lymphoepithelioma). As in squamous cell carcinoma of the nasopharynx, all seven lymphoepithelial carcinomas stained for prekeratin whereas other look-alike but histogenetically different neoplasms (malignant lymphoma, esthesioneuroblastoma, and small round cell sarcomas) did not stain. In addition to confirming the squamous epithelial nature of lymphoepithelioma, our findings indicated that immunoperoxidase staining for prekeratin is a useful diagnostic tool in the differential diagnosis of nasopharyngeal carcinoma in general and lymphoepithelioma in particular.
| Original language | English |
|---|---|
| Pages (from-to) | 588-589 |
| Number of pages | 2 |
| Journal | Archives of Pathology and Laboratory Medicine |
| Volume | 108 |
| Issue number | 7 |
| State | Published - Jan 1 1984 |
Fingerprint
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology
Cite this
Prekeratin immunohistochemistry in the diagnosis of undifferentiated carcinoma of the nasopharyngeal type. / Ziegels-Weissman, J.; Nadji, Mehrdad; Penneys, N. S.; Morales, Azorides R.
In: Archives of Pathology and Laboratory Medicine, Vol. 108, No. 7, 01.01.1984, p. 588-589.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prekeratin immunohistochemistry in the diagnosis of undifferentiated carcinoma of the nasopharyngeal type
AU - Ziegels-Weissman, J.
AU - Nadji, Mehrdad
AU - Penneys, N. S.
AU - Morales, Azorides R
PY - 1984/1/1
Y1 - 1984/1/1
N2 - We investigated the value of prekeratin immunostaining in establishing the diagnosis of undifferentiated carcinoma of the nasopharyngeal type (lymphoepithelioma). As in squamous cell carcinoma of the nasopharynx, all seven lymphoepithelial carcinomas stained for prekeratin whereas other look-alike but histogenetically different neoplasms (malignant lymphoma, esthesioneuroblastoma, and small round cell sarcomas) did not stain. In addition to confirming the squamous epithelial nature of lymphoepithelioma, our findings indicated that immunoperoxidase staining for prekeratin is a useful diagnostic tool in the differential diagnosis of nasopharyngeal carcinoma in general and lymphoepithelioma in particular.
AB - We investigated the value of prekeratin immunostaining in establishing the diagnosis of undifferentiated carcinoma of the nasopharyngeal type (lymphoepithelioma). As in squamous cell carcinoma of the nasopharynx, all seven lymphoepithelial carcinomas stained for prekeratin whereas other look-alike but histogenetically different neoplasms (malignant lymphoma, esthesioneuroblastoma, and small round cell sarcomas) did not stain. In addition to confirming the squamous epithelial nature of lymphoepithelioma, our findings indicated that immunoperoxidase staining for prekeratin is a useful diagnostic tool in the differential diagnosis of nasopharyngeal carcinoma in general and lymphoepithelioma in particular.
UR - http://www.scopus.com/inward/record.url?scp=0021240164&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021240164&partnerID=8YFLogxK
M3 - Article
C2 - 6203499
AN - SCOPUS:0021240164
VL - 108
SP - 588
EP - 589
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
SN - 0003-9985
IS - 7
ER -