Preimplantation genetic diagnosis

An overview of socio-ethical and legal considerations

Bartha M. Knoppers, Sylvie Bordet, Rosario Isasi

Research output: Chapter in Book/Report/Conference proceedingChapter

38 Citations (Scopus)

Abstract

Preimplantation genetic diagnosis (PGD) permits the selection of embryos of a particular genotype prior to implantation. As a reproductive technology involving embryo selection, PGD has become associated with considerable controversy. This review examines some of the ethical, legal, and social issues raised by PGD. Relevant ethical considerations include the status of the embryo and the interests and duties of the parents. On a social policy level, considerations of access as well as the impact of this technology on families, women, and physician's duties also warrant consideration. An analysis of these issues in the context of using PGD for selecting embryos unaffected by a serious disorder and for sex selection is presented. We also present a brief survey of PGD-related regulatory schemes in several countries, including the United Kingdom and the United States.

Original languageEnglish (US)
Title of host publicationAnnual Review of Genomics and Human Genetics
EditorsAravinda Chakravarti, Eric Green
Pages201-221
Number of pages21
DOIs
StatePublished - Oct 31 2006
Externally publishedYes

Publication series

NameAnnual Review of Genomics and Human Genetics
Volume7
ISSN (Print)1527-8204

Fingerprint

Preimplantation Diagnosis
Embryonic Structures
Sex Preselection
Women Physicians
Reproductive Techniques
Family Physicians
Public Policy
Parents
Genotype
Technology

Keywords

  • ELSI
  • Ethics
  • Policy
  • Regulation

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

Cite this

Knoppers, B. M., Bordet, S., & Isasi, R. (2006). Preimplantation genetic diagnosis: An overview of socio-ethical and legal considerations. In A. Chakravarti, & E. Green (Eds.), Annual Review of Genomics and Human Genetics (pp. 201-221). (Annual Review of Genomics and Human Genetics; Vol. 7). https://doi.org/10.1146/annurev.genom.7.080505.115753

Preimplantation genetic diagnosis : An overview of socio-ethical and legal considerations. / Knoppers, Bartha M.; Bordet, Sylvie; Isasi, Rosario.

Annual Review of Genomics and Human Genetics. ed. / Aravinda Chakravarti; Eric Green. 2006. p. 201-221 (Annual Review of Genomics and Human Genetics; Vol. 7).

Research output: Chapter in Book/Report/Conference proceedingChapter

Knoppers, BM, Bordet, S & Isasi, R 2006, Preimplantation genetic diagnosis: An overview of socio-ethical and legal considerations. in A Chakravarti & E Green (eds), Annual Review of Genomics and Human Genetics. Annual Review of Genomics and Human Genetics, vol. 7, pp. 201-221. https://doi.org/10.1146/annurev.genom.7.080505.115753
Knoppers BM, Bordet S, Isasi R. Preimplantation genetic diagnosis: An overview of socio-ethical and legal considerations. In Chakravarti A, Green E, editors, Annual Review of Genomics and Human Genetics. 2006. p. 201-221. (Annual Review of Genomics and Human Genetics). https://doi.org/10.1146/annurev.genom.7.080505.115753
Knoppers, Bartha M. ; Bordet, Sylvie ; Isasi, Rosario. / Preimplantation genetic diagnosis : An overview of socio-ethical and legal considerations. Annual Review of Genomics and Human Genetics. editor / Aravinda Chakravarti ; Eric Green. 2006. pp. 201-221 (Annual Review of Genomics and Human Genetics).
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