Prehypertension is real and can be associated with target organ damage

Barry J. Materson, Manuel Garcia-Estrada, Stephane B. Degraff, Richard A. Preston

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Prehypertension (systolic blood pressure 120–139 or diastolic blood pressure 80–89 mm Hg) confers a risk of progression to hypertension, impairment of cognitive function, increased left ventricular mass, risk of end-stage renal disease, and an association with arteriosclerosis. Recent studies provide data that could support the rationale for treating prehypertensives subjects with antihypertensive medications in addition to lifestyle modification, especially if they have concomitant cardiovascular risk factors.

Original languageEnglish (US)
Pages (from-to)704-708
Number of pages5
JournalJournal of the American Society of Hypertension
Issue number11
StatePublished - Nov 2017


  • Cognitive function
  • drug treatment
  • end-stage renal disease
  • left ventricular hypertrophy

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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