Pregnancy-induced hypertension and early neonatal death: A case-control study

J. Zhang, W. W. Cai, D. J. Lee

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Literature on the association between pregnancy-induced hypertension and early neonatal death is limited. The present case-control study consisted of 342 early neonatal deaths and 523 frequency-matched controls. After controlling for other factors such as infant sex, gravidity, maternal age, threatened abortion, and maternal anemia, moderate to severe pregnancy- induced hypertension was associated with an increased risk of early neonatal death with apparent dose-effect gradients (odds ratio = 1.8 for moderate and 2.2 for severe). The biologic plausibility of pregnancy-induced hypertension as a cause of neonatal mortality is discussed.

Original languageEnglish (US)
Pages (from-to)401-403
Number of pages3
JournalAmerican Journal of Perinatology
Issue number5
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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