Abstract
Aims: Examine the validity of preference-weighted health-related quality of life measures in a sample of substance use disorder (SUD) patients. The implications of cost-utility analyses (CUAs) of SUD interventions are discussed. Design: Cross-sectional analysis of subjects seeking SUD treatment. Setting: Seven SUD treatment centers in a medium-sized Midwestern metropolitan area in the United States. Participants: Data from 574 SUD subjects were analyzed from a study to test interventions to improve linkage and engagement with substance abuse treatment. Measurements: Subjects completed the following preference-weighted measures: self-administered Quality of Well-Being scale (QWB-SA) and Medical Outcomes Study SF-12 (standard gamble weighted or SF-12 SG); and clinical measures: Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Findings: In unadjusted analyses, the QWB-SA was correlated significantly with six of seven ASI subscales and the SF-12 SG was correlated with four of seven. In adjusted analyses, both preference-weighted measures were significantly correlated with diagnostic, physical health, mental health and drug use measures, but not with legal or alcohol use measures. The QWB-SA was also correlated with employment problems and the SF-12 SG was correlated with family/social problems. Conclusions: This study generally supports the construct validity of preference-weighted health-related quality of life measures in SUD patients. However, the QWB-SA and SF-12 SG did not correlate with all ASI scales. Cost-benefit analysis may be preferable when policy-makers are interested in evaluating the full range of SUD intervention outcomes.
| Original language | English |
|---|---|
| Pages (from-to) | 1320-1329 |
| Number of pages | 10 |
| Journal | Addiction |
| Volume | 103 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 1 2008 |
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Keywords
- Cost-effectiveness analysis
- Cost-utility analysis
- Health-related quality of life
- Quality of wellbeing scale
- SF-12 scale
- Substance use disorder
ASJC Scopus subject areas
- Medicine (miscellaneous)
Cite this
Preference-weighted health-related quality of life measures and substance use disorder severity. / Pyne, Jeffrey M.; French, Michael; McCollister, Kathryn; Tripathi, Shanti; Rapp, Richard; Booth, Brenda.
In: Addiction, Vol. 103, No. 8, 01.08.2008, p. 1320-1329.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preference-weighted health-related quality of life measures and substance use disorder severity
AU - Pyne, Jeffrey M.
AU - French, Michael
AU - McCollister, Kathryn
AU - Tripathi, Shanti
AU - Rapp, Richard
AU - Booth, Brenda
PY - 2008/8/1
Y1 - 2008/8/1
N2 - Aims: Examine the validity of preference-weighted health-related quality of life measures in a sample of substance use disorder (SUD) patients. The implications of cost-utility analyses (CUAs) of SUD interventions are discussed. Design: Cross-sectional analysis of subjects seeking SUD treatment. Setting: Seven SUD treatment centers in a medium-sized Midwestern metropolitan area in the United States. Participants: Data from 574 SUD subjects were analyzed from a study to test interventions to improve linkage and engagement with substance abuse treatment. Measurements: Subjects completed the following preference-weighted measures: self-administered Quality of Well-Being scale (QWB-SA) and Medical Outcomes Study SF-12 (standard gamble weighted or SF-12 SG); and clinical measures: Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Findings: In unadjusted analyses, the QWB-SA was correlated significantly with six of seven ASI subscales and the SF-12 SG was correlated with four of seven. In adjusted analyses, both preference-weighted measures were significantly correlated with diagnostic, physical health, mental health and drug use measures, but not with legal or alcohol use measures. The QWB-SA was also correlated with employment problems and the SF-12 SG was correlated with family/social problems. Conclusions: This study generally supports the construct validity of preference-weighted health-related quality of life measures in SUD patients. However, the QWB-SA and SF-12 SG did not correlate with all ASI scales. Cost-benefit analysis may be preferable when policy-makers are interested in evaluating the full range of SUD intervention outcomes.
AB - Aims: Examine the validity of preference-weighted health-related quality of life measures in a sample of substance use disorder (SUD) patients. The implications of cost-utility analyses (CUAs) of SUD interventions are discussed. Design: Cross-sectional analysis of subjects seeking SUD treatment. Setting: Seven SUD treatment centers in a medium-sized Midwestern metropolitan area in the United States. Participants: Data from 574 SUD subjects were analyzed from a study to test interventions to improve linkage and engagement with substance abuse treatment. Measurements: Subjects completed the following preference-weighted measures: self-administered Quality of Well-Being scale (QWB-SA) and Medical Outcomes Study SF-12 (standard gamble weighted or SF-12 SG); and clinical measures: Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Findings: In unadjusted analyses, the QWB-SA was correlated significantly with six of seven ASI subscales and the SF-12 SG was correlated with four of seven. In adjusted analyses, both preference-weighted measures were significantly correlated with diagnostic, physical health, mental health and drug use measures, but not with legal or alcohol use measures. The QWB-SA was also correlated with employment problems and the SF-12 SG was correlated with family/social problems. Conclusions: This study generally supports the construct validity of preference-weighted health-related quality of life measures in SUD patients. However, the QWB-SA and SF-12 SG did not correlate with all ASI scales. Cost-benefit analysis may be preferable when policy-makers are interested in evaluating the full range of SUD intervention outcomes.
KW - Cost-effectiveness analysis
KW - Cost-utility analysis
KW - Health-related quality of life
KW - Quality of wellbeing scale
KW - SF-12 scale
KW - Substance use disorder
UR - http://www.scopus.com/inward/record.url?scp=47549118905&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=47549118905&partnerID=8YFLogxK
U2 - 10.1111/j.1360-0443.2008.02153.x
DO - 10.1111/j.1360-0443.2008.02153.x
M3 - Article
C2 - 18397359
AN - SCOPUS:47549118905
VL - 103
SP - 1320
EP - 1329
JO - Addiction
JF - Addiction
SN - 0965-2140
IS - 8
ER -