Predominance of type II collagen in synovial chrondromatosis

L. M. Ryan, Herman S Cheung, J. P. Schwab, R. P. Johnson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Synovial chondromas histologically consist of mature chondrocytes surrounded by metaplastic synovial lining cells and synovium. Chondromas from a patient who had synovial chondromatosis were isolated and collagen type determined by SDS gel electrophoresis and differential salt precipitation, and cyanogen bromide peptide analysis. Chondromas contained 90% Type II collagen. This collagen profile supports chondroma matrix production by chondrocytes originating from biochemically as well as histologically metaplastic subsynovial cells, or by chondrocytes derived from articular hyaline cartilage.

Original languageEnglish
Pages (from-to)173-177
Number of pages5
JournalClinical Orthopaedics and Related Research
VolumeNo.168
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Chondroma
Collagen Type II
Chondrocytes
Collagen
Synovial Chondromatosis
Hyaline Cartilage
Cyanogen Bromide
Synovial Membrane
Articular Cartilage
Electrophoresis
Salts
Gels
Peptides

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Predominance of type II collagen in synovial chrondromatosis. / Ryan, L. M.; Cheung, Herman S; Schwab, J. P.; Johnson, R. P.

In: Clinical Orthopaedics and Related Research, Vol. No.168, 01.01.1982, p. 173-177.

Research output: Contribution to journalArticle

Ryan, L. M. ; Cheung, Herman S ; Schwab, J. P. ; Johnson, R. P. / Predominance of type II collagen in synovial chrondromatosis. In: Clinical Orthopaedics and Related Research. 1982 ; Vol. No.168. pp. 173-177.
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