Predictors of the long-term course of comorbid PTSD: A naturalistic prospective study

Carlos Perez Benitez, Caron Zlotnick, Ingrid Dyck, Robert Stout, Erica Angert, Risa Weisberg, Martin Keller

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives. The study examined the long-term course of posttraumatic stress disorder (PTSD) by analyzing rates of recurrence and the predictive value of comorbid psychiatric disorders and psychosocial functioning. Methods. This study is based on diagnostic assessments administered at intake and subsequent follow-up interviews over a period of 15 years in a sample of 90 anxiety-disordered patients with comorbid PTSD who participated in the Harvard Brown Anxiety Research project (HARP). KaplanMeier life table analysis revealed a 0.20 probability of full remission during the 15 years of follow-up. Results. Latent growth model (LGM) analysis revealed that the number of trauma exposures was a predictor of a worse course of PTSD but only during some intervals of the 15-year follow-up. Subjects with full social phobia were more likely to experience worsening of PTSD over time in comparison with subjects with less severe social phobia. Role functioning in the areas of household and employment was a significant predictor of a declining course of PTSD. Conclusions. These findings revealed the dynamic nature of the predictive value of traumatic experiences, the deleterious effect of social phobia and the long term effect of psychosocial functioning on the course of PTSD. Implications for treatment planning and development of interventions for PTSD are discussed.

Original languageEnglish
Pages (from-to)232-237
Number of pages6
JournalInternational Journal of Psychiatry in Clinical Practice
Volume17
Issue number3
DOIs
StatePublished - Aug 1 2013

Fingerprint

Post-Traumatic Stress Disorders
Prospective Studies
Anxiety
Life Tables
Psychiatry
Interviews
Recurrence
Wounds and Injuries
Growth
Research
Social Phobia

Keywords

  • Clinical predictors of PTSD
  • Long-term course
  • Longitudin al studies
  • Psychosocial functioning
  • PTSD
  • Social anxiety

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Predictors of the long-term course of comorbid PTSD : A naturalistic prospective study. / Perez Benitez, Carlos; Zlotnick, Caron; Dyck, Ingrid; Stout, Robert; Angert, Erica; Weisberg, Risa; Keller, Martin.

In: International Journal of Psychiatry in Clinical Practice, Vol. 17, No. 3, 01.08.2013, p. 232-237.

Research output: Contribution to journalArticle

Perez Benitez, C, Zlotnick, C, Dyck, I, Stout, R, Angert, E, Weisberg, R & Keller, M 2013, 'Predictors of the long-term course of comorbid PTSD: A naturalistic prospective study', International Journal of Psychiatry in Clinical Practice, vol. 17, no. 3, pp. 232-237. https://doi.org/10.3109/13651501.2012.667113
Perez Benitez, Carlos ; Zlotnick, Caron ; Dyck, Ingrid ; Stout, Robert ; Angert, Erica ; Weisberg, Risa ; Keller, Martin. / Predictors of the long-term course of comorbid PTSD : A naturalistic prospective study. In: International Journal of Psychiatry in Clinical Practice. 2013 ; Vol. 17, No. 3. pp. 232-237.
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