Predictors of necrospermia in men with spinal cord injury

Nancy Brackett, William E. Bloch, Charles M Lynne

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Purpose: We identify predictors of the lowest yield of dead sperm in ejaculates of men with spinal cord injury. Materials and Methods: The percentages of dead immotile sperm and dead total sperm were compared in 141 spinal cord injured and 52 normal men. Predictors of necrospermia investigated in spinal cord injured men included specimen collection by vibratory stimulation versus electroejaculation, residence of sperm in antegrade versus retrograde specimens and level of injury. Results: Spinal cord injured subjects had a significantly higher percentage of dead sperm in the immotile fraction and total specimen than control subjects. The percentage of dead sperm was lower in antegrade versus retrograde specimens and in specimens produced by vibratory stimulation versus electroejaculation. There was no difference in the percentage of dead sperm by level of injury. Conclusions: Of the parameters evaluated only method and type of specimen collection were predictive of the degree of necrospermia in men with spinal cord injury. Level of injury was not predictive. The ratio of dead-to-live immotile sperm in spinal cord injured men was double that in normal men, indicating a pathological mechanism for sperm cell death.

Original languageEnglish
Pages (from-to)844-847
Number of pages4
JournalJournal of Urology
Volume159
Issue number3
DOIs
StatePublished - Mar 1 1998

Fingerprint

Spinal Cord Injuries
Spermatozoa
Spinal Cord
Specimen Handling
Wounds and Injuries
Cell Death

Keywords

  • Cell movement
  • Spermatozoa
  • Spinal cord injuries
  • Testis

ASJC Scopus subject areas

  • Urology

Cite this

Predictors of necrospermia in men with spinal cord injury. / Brackett, Nancy; Bloch, William E.; Lynne, Charles M.

In: Journal of Urology, Vol. 159, No. 3, 01.03.1998, p. 844-847.

Research output: Contribution to journalArticle

Brackett, Nancy ; Bloch, William E. ; Lynne, Charles M. / Predictors of necrospermia in men with spinal cord injury. In: Journal of Urology. 1998 ; Vol. 159, No. 3. pp. 844-847.
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