Abstract
Over the last quarter century there has been significant progress toward identifying certain characteristics and patterns in GBM patients to predict survival times and outcomes. We sought to identify clinical predictors of survival in GBM patients from the past 24 years. We examined patient survival related to tumor locations, surgical treatment, postoperative course, radiotherapy, chemotherapy, patient age, GBM recurrence, imaging characteristics, serum, and molecular markers. We present predictors that may increase, decrease, or play no significant role in determining a GBM patient's long-term survival or affect the quality of life.
| Original language | English |
|---|---|
| Pages (from-to) | 287-308 |
| Number of pages | 22 |
| Journal | Cancer Investigation |
| Volume | 31 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jun 1 2013 |
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Keywords
- Brain tumors
- Cancer biomarkers
- CNS malignancy
- Glioblastoma multiforme
- Prognosis and response
- Systematic analysis
- Treatment
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Predictors of long-term survival in patients with glioblastoma multiforme : Advancements from the last quarter century. / Chaudhry, Nauman S.; Shah, Ashish H.; Ferraro, Nicholas; Snelling, Brian M.; Bregy, Amade; Madhavan, Karthik; Komotar, Ricardo J.
In: Cancer Investigation, Vol. 31, No. 5, 01.06.2013, p. 287-308.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Predictors of long-term survival in patients with glioblastoma multiforme
T2 - Advancements from the last quarter century
AU - Chaudhry, Nauman S.
AU - Shah, Ashish H.
AU - Ferraro, Nicholas
AU - Snelling, Brian M.
AU - Bregy, Amade
AU - Madhavan, Karthik
AU - Komotar, Ricardo J
PY - 2013/6/1
Y1 - 2013/6/1
N2 - Over the last quarter century there has been significant progress toward identifying certain characteristics and patterns in GBM patients to predict survival times and outcomes. We sought to identify clinical predictors of survival in GBM patients from the past 24 years. We examined patient survival related to tumor locations, surgical treatment, postoperative course, radiotherapy, chemotherapy, patient age, GBM recurrence, imaging characteristics, serum, and molecular markers. We present predictors that may increase, decrease, or play no significant role in determining a GBM patient's long-term survival or affect the quality of life.
AB - Over the last quarter century there has been significant progress toward identifying certain characteristics and patterns in GBM patients to predict survival times and outcomes. We sought to identify clinical predictors of survival in GBM patients from the past 24 years. We examined patient survival related to tumor locations, surgical treatment, postoperative course, radiotherapy, chemotherapy, patient age, GBM recurrence, imaging characteristics, serum, and molecular markers. We present predictors that may increase, decrease, or play no significant role in determining a GBM patient's long-term survival or affect the quality of life.
KW - Brain tumors
KW - Cancer biomarkers
KW - CNS malignancy
KW - Glioblastoma multiforme
KW - Prognosis and response
KW - Systematic analysis
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=84877960698&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84877960698&partnerID=8YFLogxK
U2 - 10.3109/07357907.2013.789899
DO - 10.3109/07357907.2013.789899
M3 - Article
VL - 31
SP - 287
EP - 308
JO - Cancer Investigation
JF - Cancer Investigation
SN - 0735-7907
IS - 5
ER -