Abstract
Over the last quarter century there has been significant progress toward identifying certain characteristics and patterns in GBM patients to predict survival times and outcomes. We sought to identify clinical predictors of survival in GBM patients from the past 24 years. We examined patient survival related to tumor locations, surgical treatment, postoperative course, radiotherapy, chemotherapy, patient age, GBM recurrence, imaging characteristics, serum, and molecular markers. We present predictors that may increase, decrease, or play no significant role in determining a GBM patient's long-term survival or affect the quality of life.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 287-308 |
| Number of pages | 22 |
| Journal | Cancer Investigation |
| Volume | 31 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jun 2013 |
Keywords
- Brain tumors
- Cancer biomarkers
- CNS malignancy
- Glioblastoma multiforme
- Prognosis and response
- Systematic analysis
- Treatment
ASJC Scopus subject areas
- Cancer Research
- Oncology
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Cite this
Chaudhry, N. S., Shah, A. H., Ferraro, N., Snelling, B. M., Bregy, A., Madhavan, K., & Komotar, R. J. (2013). Predictors of long-term survival in patients with glioblastoma multiforme: Advancements from the last quarter century. Cancer Investigation, 31(5), 287-308. https://doi.org/10.3109/07357907.2013.789899