Prediction of quality of life and survival after surgery for symptomatic spinal metastases: A multicenter cohort study to determine suitability for surgical treatment

David Choi, Zoe Fox, Todd Albert, Mark Arts, Laurent Balabaud, Cody Bunger, Jacob M. Buchowski, Maarten H. Coppes, Bart Depreitere, Michael G. Fehlings, James Harrop, Norio Kawahara, Juan A. Martin-Benlloch, Eric M. Massicotte, Christian Mazel, Fetullah C. Oner, Wilco Peul, Nasir Quraishi, Yasuaki Tokuhashi, Katsuro TomitaJorit Jan Verlaan, Michael Wang, H. Alan Crockard

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

BACKGROUND: Surgery for symptomatic spinal metastases aims to improve quality of life, pain, function, and stability. Complications in the postoperative period are not uncommon; therefore, it is important to select appropriate patients who are likely to benefit the greatest from surgery. Previous studies have focused on predicting survival rather than quality of life after surgery. OBJECTIVE: To determine preoperative patient characteristics that predict postoperative quality of life and survival in patients who undergo surgery for spinal metastases. METHODS: In a prospective cohort study of 922 patients with spinal metastases who underwent surgery, we performed preoperative and postoperative assessment of EuroQol EQ-5D quality of life, visual analog score for pain, Karnofsky physical functioning score, complication rates, and survival. RESULTS: The primary tumor type, number of spinal metastases, and presence of visceral metastases were independent predictors of survival. Predictors of quality of life after surgery included preoperative EQ-5D (P .002), Frankel score (P

Original languageEnglish (US)
Pages (from-to)698-708
Number of pages11
JournalNeurosurgery
Volume77
Issue number5
DOIs
StatePublished - Aug 4 2015
Externally publishedYes

Fingerprint

Multicenter Studies
Cohort Studies
Quality of Life
Neoplasm Metastasis
Survival
Therapeutics
Pain
Postoperative Period
Survival Rate
Prospective Studies
Neoplasms

Keywords

  • Prognosis
  • Quality of life
  • Spinal metastases
  • Surgery
  • Survival

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Prediction of quality of life and survival after surgery for symptomatic spinal metastases : A multicenter cohort study to determine suitability for surgical treatment. / Choi, David; Fox, Zoe; Albert, Todd; Arts, Mark; Balabaud, Laurent; Bunger, Cody; Buchowski, Jacob M.; Coppes, Maarten H.; Depreitere, Bart; Fehlings, Michael G.; Harrop, James; Kawahara, Norio; Martin-Benlloch, Juan A.; Massicotte, Eric M.; Mazel, Christian; Oner, Fetullah C.; Peul, Wilco; Quraishi, Nasir; Tokuhashi, Yasuaki; Tomita, Katsuro; Verlaan, Jorit Jan; Wang, Michael; Crockard, H. Alan.

In: Neurosurgery, Vol. 77, No. 5, 04.08.2015, p. 698-708.

Research output: Contribution to journalArticle

Choi, D, Fox, Z, Albert, T, Arts, M, Balabaud, L, Bunger, C, Buchowski, JM, Coppes, MH, Depreitere, B, Fehlings, MG, Harrop, J, Kawahara, N, Martin-Benlloch, JA, Massicotte, EM, Mazel, C, Oner, FC, Peul, W, Quraishi, N, Tokuhashi, Y, Tomita, K, Verlaan, JJ, Wang, M & Crockard, HA 2015, 'Prediction of quality of life and survival after surgery for symptomatic spinal metastases: A multicenter cohort study to determine suitability for surgical treatment', Neurosurgery, vol. 77, no. 5, pp. 698-708. https://doi.org/10.1227/NEU.0000000000000907
Choi, David ; Fox, Zoe ; Albert, Todd ; Arts, Mark ; Balabaud, Laurent ; Bunger, Cody ; Buchowski, Jacob M. ; Coppes, Maarten H. ; Depreitere, Bart ; Fehlings, Michael G. ; Harrop, James ; Kawahara, Norio ; Martin-Benlloch, Juan A. ; Massicotte, Eric M. ; Mazel, Christian ; Oner, Fetullah C. ; Peul, Wilco ; Quraishi, Nasir ; Tokuhashi, Yasuaki ; Tomita, Katsuro ; Verlaan, Jorit Jan ; Wang, Michael ; Crockard, H. Alan. / Prediction of quality of life and survival after surgery for symptomatic spinal metastases : A multicenter cohort study to determine suitability for surgical treatment. In: Neurosurgery. 2015 ; Vol. 77, No. 5. pp. 698-708.
@article{a2ed651b7b364be0bb03dd9d450054b4,
title = "Prediction of quality of life and survival after surgery for symptomatic spinal metastases: A multicenter cohort study to determine suitability for surgical treatment",
abstract = "BACKGROUND: Surgery for symptomatic spinal metastases aims to improve quality of life, pain, function, and stability. Complications in the postoperative period are not uncommon; therefore, it is important to select appropriate patients who are likely to benefit the greatest from surgery. Previous studies have focused on predicting survival rather than quality of life after surgery. OBJECTIVE: To determine preoperative patient characteristics that predict postoperative quality of life and survival in patients who undergo surgery for spinal metastases. METHODS: In a prospective cohort study of 922 patients with spinal metastases who underwent surgery, we performed preoperative and postoperative assessment of EuroQol EQ-5D quality of life, visual analog score for pain, Karnofsky physical functioning score, complication rates, and survival. RESULTS: The primary tumor type, number of spinal metastases, and presence of visceral metastases were independent predictors of survival. Predictors of quality of life after surgery included preoperative EQ-5D (P .002), Frankel score (P",
keywords = "Prognosis, Quality of life, Spinal metastases, Surgery, Survival",
author = "David Choi and Zoe Fox and Todd Albert and Mark Arts and Laurent Balabaud and Cody Bunger and Buchowski, {Jacob M.} and Coppes, {Maarten H.} and Bart Depreitere and Fehlings, {Michael G.} and James Harrop and Norio Kawahara and Martin-Benlloch, {Juan A.} and Massicotte, {Eric M.} and Christian Mazel and Oner, {Fetullah C.} and Wilco Peul and Nasir Quraishi and Yasuaki Tokuhashi and Katsuro Tomita and Verlaan, {Jorit Jan} and Michael Wang and Crockard, {H. Alan}",
year = "2015",
month = "8",
day = "4",
doi = "10.1227/NEU.0000000000000907",
language = "English (US)",
volume = "77",
pages = "698--708",
journal = "Neurosurgery",
issn = "0148-396X",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - Prediction of quality of life and survival after surgery for symptomatic spinal metastases

T2 - A multicenter cohort study to determine suitability for surgical treatment

AU - Choi, David

AU - Fox, Zoe

AU - Albert, Todd

AU - Arts, Mark

AU - Balabaud, Laurent

AU - Bunger, Cody

AU - Buchowski, Jacob M.

AU - Coppes, Maarten H.

AU - Depreitere, Bart

AU - Fehlings, Michael G.

AU - Harrop, James

AU - Kawahara, Norio

AU - Martin-Benlloch, Juan A.

AU - Massicotte, Eric M.

AU - Mazel, Christian

AU - Oner, Fetullah C.

AU - Peul, Wilco

AU - Quraishi, Nasir

AU - Tokuhashi, Yasuaki

AU - Tomita, Katsuro

AU - Verlaan, Jorit Jan

AU - Wang, Michael

AU - Crockard, H. Alan

PY - 2015/8/4

Y1 - 2015/8/4

N2 - BACKGROUND: Surgery for symptomatic spinal metastases aims to improve quality of life, pain, function, and stability. Complications in the postoperative period are not uncommon; therefore, it is important to select appropriate patients who are likely to benefit the greatest from surgery. Previous studies have focused on predicting survival rather than quality of life after surgery. OBJECTIVE: To determine preoperative patient characteristics that predict postoperative quality of life and survival in patients who undergo surgery for spinal metastases. METHODS: In a prospective cohort study of 922 patients with spinal metastases who underwent surgery, we performed preoperative and postoperative assessment of EuroQol EQ-5D quality of life, visual analog score for pain, Karnofsky physical functioning score, complication rates, and survival. RESULTS: The primary tumor type, number of spinal metastases, and presence of visceral metastases were independent predictors of survival. Predictors of quality of life after surgery included preoperative EQ-5D (P .002), Frankel score (P

AB - BACKGROUND: Surgery for symptomatic spinal metastases aims to improve quality of life, pain, function, and stability. Complications in the postoperative period are not uncommon; therefore, it is important to select appropriate patients who are likely to benefit the greatest from surgery. Previous studies have focused on predicting survival rather than quality of life after surgery. OBJECTIVE: To determine preoperative patient characteristics that predict postoperative quality of life and survival in patients who undergo surgery for spinal metastases. METHODS: In a prospective cohort study of 922 patients with spinal metastases who underwent surgery, we performed preoperative and postoperative assessment of EuroQol EQ-5D quality of life, visual analog score for pain, Karnofsky physical functioning score, complication rates, and survival. RESULTS: The primary tumor type, number of spinal metastases, and presence of visceral metastases were independent predictors of survival. Predictors of quality of life after surgery included preoperative EQ-5D (P .002), Frankel score (P

KW - Prognosis

KW - Quality of life

KW - Spinal metastases

KW - Surgery

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=84944675260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944675260&partnerID=8YFLogxK

U2 - 10.1227/NEU.0000000000000907

DO - 10.1227/NEU.0000000000000907

M3 - Article

AN - SCOPUS:84944675260

VL - 77

SP - 698

EP - 708

JO - Neurosurgery

JF - Neurosurgery

SN - 0148-396X

IS - 5

ER -