Prediction of malignancy using transvaginal color flow Doppler in patients with gynecologic tumors

J. R. Carter, J. M. Fowler, J. W. Carlson, L. F. Carson, L. L. Adcock, L. B. Twiggs

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Eighty-five patients referred to the Women's Cancer Center, University of Minnesota had transvaginal color flow Doppler performed to determine if pelvic malignancy could be predicted by blood flow assessment. Their mean age was 49 years (range 21-86 years). Thirty-five patients were subsequently found to have malignant tumors of the cervix, uterus or ovary. The presence of increased intratumoral blood flow as depicted by color flow Doppler had a sensitivity of 83%, specificity of 100%, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 89% for malignancy. The mean intratumoral Pulsatility Index (PI) of the patients with malignant tumors was 0.81 (SD 0.24; range 0.3-1.2), which was significantly lower than for the benign group (P = 0.001). A PI of ≤1.0 had a sensitivity of 96.3%, specificity of 94.3%, PPV of 89.7% and NPV of 98% for predicting malignancy. Transvaginal color flow Doppler shows promise as a method of predicting malignancy in patients with gynecologic pathology.

Original languageEnglish
Pages (from-to)279-284
Number of pages6
JournalInternational Journal of Gynecological Cancer
Volume3
Issue number5
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

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Color
Neoplasms
Sensitivity and Specificity
Cervix Uteri
Ovary
Pathology

ASJC Scopus subject areas

  • Cancer Research
  • Obstetrics and Gynecology
  • Oncology

Cite this

Prediction of malignancy using transvaginal color flow Doppler in patients with gynecologic tumors. / Carter, J. R.; Fowler, J. M.; Carlson, J. W.; Carson, L. F.; Adcock, L. L.; Twiggs, L. B.

In: International Journal of Gynecological Cancer, Vol. 3, No. 5, 01.01.1993, p. 279-284.

Research output: Contribution to journalArticle

Carter, J. R. ; Fowler, J. M. ; Carlson, J. W. ; Carson, L. F. ; Adcock, L. L. ; Twiggs, L. B. / Prediction of malignancy using transvaginal color flow Doppler in patients with gynecologic tumors. In: International Journal of Gynecological Cancer. 1993 ; Vol. 3, No. 5. pp. 279-284.
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