Prediction of disability in schizophrenia: Symptoms, cognition, and self-assessment

Philip D. Harvey, Martin T. Strassnig, Juliet Silberstein

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


Schizophrenia is associated with wide-ranging disability across multiple functional domains. There are several determinants of disability that have been identified to date, including cognitive and social cognitive impairments, impairments in everyday functional skills and social skills, difficulties in self-assessment of abilities, and negative symptoms. These impairments are related to different elements of disability, and disability and its predictors are not a single global dimension. Further, although psychotic symptoms have limited cross-sectional correlations with everyday functioning, emerging evidence suggests that long-term clinical stability, often induced through treatment with long-acting antipsychotic medications, is also associated with improvements in everyday functioning. This review addresses the characteristics and origins of disability, with treatment implications noted in each disability domains.

Original languageEnglish (US)
JournalJournal of Experimental Psychopathology
Issue number3
StatePublished - Jul 2019


  • cognition
  • disability
  • psychosis
  • schizophrenia

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health


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