Precursor B-cell lymphoblastic lymphoma/leukemia presenting as osteoblastic bone lesions

Monica Recine, Amilcar A. Castellano-Sanchez, Jerome Sheldon, Michael Schwartz, Beria Cabello-Inchausti

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Lymphoblastic lymphoma is a neoplasm of precursors lymphoid cells morphologically indistinguishable from those of acute lymphoblastic leukemia. Approximately 10% to 20% of cases are of the precursor B-cell (P-BLL) phenotype. This type of lymphoma most often manifests in the skin and lymph nodes. In recent years more case reports of P-BLL presenting as lytic bone lesions have appeared in the literature. We describe an interesting case of P-BLL/leukemia that initially presented as an osteoblastic bone lesion and discuss the differential diagnosis from a pathologic-radiologic standpoint.

Original languageEnglish (US)
Pages (from-to)236-243
Number of pages8
JournalAnnals of Diagnostic Pathology
Issue number4
StatePublished - Aug 2002


  • Blastic bone
  • Lytic bone lesions
  • Pre B lymphoblastic lymphoma
  • Primary lymphoma of bone
  • Small round cell tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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