Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease

Nicholas P. Cherup, Andrew N.L. Buskard, Keri L. Strand, Kirk B. Roberson, Emma R. Michiels, Jessica E. Kuhn, Francisco A. Lopez, Joseph F. Signorile

Research output: Contribution to journalArticle

Abstract

Background: Declines in strength and power are cardinal symptoms of Parkinson's disease (PD), a progressive neuromuscular disorder. Progressive resistance training (PRT) has been shown to reduce a wide variety of PD-related motor deficits; however, no study has examined differences between the two most common RT methodologies utilized in this population, high-load, low velocity strength training (ST) and low-load, high-velocity power training (PT). The primary purpose of this study was to compare the effects of ST and PT on measures of strength, power, balance and functional movement in persons with PD. Method: Thirty-five persons with mild to moderate PD (Hoehm and Yahr Stages = 1–3; UPDRS Part III = 30.6 ± 14.0) were randomized into either a ST or PT group involving 12 weeks of supervised PRT (2 visits per week). Leg press (LP) and chest press (CP) muscular strength (1RM) and muscular peak power (PP) were assessed before and after the twelve week training period as primary outcome measures. In addition, secondary measures of balance (Berg Balance Assessment (BBA), dynamic posturography (DMA), Modified Falls Efficacy Scale (MFES)), functional movement (timed up-and-go), and quality of life (PDQ-39 summary index and Mobility subscore) were obtained at the same time points, given the impact of PD symptoms on fall probability and independence. Results: Repeated measures ANCOVA revealed significant improvements in LP 1RM (Mdiff = 54.89 kg, 95% CI: 43.38, 66.40; p < .05; d = 3.38) and CP 1RM (Mdiff = 7.33 kg, 95% CI: 4.75, 9.91; p < .05; d = 2.02). Additionally, significant improvements were seen in LPPP (Mdiff = 112.27 W, 95% CI: 56.03, 168.51; p < .05; d = 1.42) and CPPP (Mdiff = 52.1 W, 95% CI: 23.38, 80.86; p = .001; d = 1.29). No significant improvements were seen for any secondary outcome measures, however BBA scores were shown to significantly decrease following the intervention (Mdiff = −1.686, 95% CI: −2.89, −0.482; p = .007 d = −0.96), although this change did not reach clinical significance (clinically meaningful change = ±4.0). In addition, the ST group demonstrated significantly poorer PDQ-39SI scores (Mdiff = 4.96, 95% CI: 0.54, 9.38; p = .029), whereas the entire sample showed significantly poorer PDQ-39MOB scores (Mdiff = 4.80, 95% CI: 0.17, 9.43; p = .043; d = 0.71). Conclusions: Both ST and PT appear to be effective at reducing the neuromuscular deficits associated with PD; however, the use of these interventions for improving functional performance was not supported.

Original languageEnglish (US)
Article number110740
JournalExperimental Gerontology
Volume128
DOIs
StatePublished - Dec 2019

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Resistance Training
Parkinson Disease
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Outcome Assessment (Health Care)
Quality of Life
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Population

Keywords

  • High-velocity training
  • Neuromuscular function
  • Pneumatic resistance
  • Resistance training

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology

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Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease. / Cherup, Nicholas P.; Buskard, Andrew N.L.; Strand, Keri L.; Roberson, Kirk B.; Michiels, Emma R.; Kuhn, Jessica E.; Lopez, Francisco A.; Signorile, Joseph F.

In: Experimental Gerontology, Vol. 128, 110740, 12.2019.

Research output: Contribution to journalArticle

Cherup, Nicholas P. ; Buskard, Andrew N.L. ; Strand, Keri L. ; Roberson, Kirk B. ; Michiels, Emma R. ; Kuhn, Jessica E. ; Lopez, Francisco A. ; Signorile, Joseph F. / Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease. In: Experimental Gerontology. 2019 ; Vol. 128.
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title = "Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease",
abstract = "Background: Declines in strength and power are cardinal symptoms of Parkinson's disease (PD), a progressive neuromuscular disorder. Progressive resistance training (PRT) has been shown to reduce a wide variety of PD-related motor deficits; however, no study has examined differences between the two most common RT methodologies utilized in this population, high-load, low velocity strength training (ST) and low-load, high-velocity power training (PT). The primary purpose of this study was to compare the effects of ST and PT on measures of strength, power, balance and functional movement in persons with PD. Method: Thirty-five persons with mild to moderate PD (Hoehm and Yahr Stages = 1–3; UPDRS Part III = 30.6 ± 14.0) were randomized into either a ST or PT group involving 12 weeks of supervised PRT (2 visits per week). Leg press (LP) and chest press (CP) muscular strength (1RM) and muscular peak power (PP) were assessed before and after the twelve week training period as primary outcome measures. In addition, secondary measures of balance (Berg Balance Assessment (BBA), dynamic posturography (DMA), Modified Falls Efficacy Scale (MFES)), functional movement (timed up-and-go), and quality of life (PDQ-39 summary index and Mobility subscore) were obtained at the same time points, given the impact of PD symptoms on fall probability and independence. Results: Repeated measures ANCOVA revealed significant improvements in LP 1RM (Mdiff = 54.89 kg, 95{\%} CI: 43.38, 66.40; p < .05; d = 3.38) and CP 1RM (Mdiff = 7.33 kg, 95{\%} CI: 4.75, 9.91; p < .05; d = 2.02). Additionally, significant improvements were seen in LPPP (Mdiff = 112.27 W, 95{\%} CI: 56.03, 168.51; p < .05; d = 1.42) and CPPP (Mdiff = 52.1 W, 95{\%} CI: 23.38, 80.86; p = .001; d = 1.29). No significant improvements were seen for any secondary outcome measures, however BBA scores were shown to significantly decrease following the intervention (Mdiff = −1.686, 95{\%} CI: −2.89, −0.482; p = .007 d = −0.96), although this change did not reach clinical significance (clinically meaningful change = ±4.0). In addition, the ST group demonstrated significantly poorer PDQ-39SI scores (Mdiff = 4.96, 95{\%} CI: 0.54, 9.38; p = .029), whereas the entire sample showed significantly poorer PDQ-39MOB scores (Mdiff = 4.80, 95{\%} CI: 0.17, 9.43; p = .043; d = 0.71). Conclusions: Both ST and PT appear to be effective at reducing the neuromuscular deficits associated with PD; however, the use of these interventions for improving functional performance was not supported.",
keywords = "High-velocity training, Neuromuscular function, Pneumatic resistance, Resistance training",
author = "Cherup, {Nicholas P.} and Buskard, {Andrew N.L.} and Strand, {Keri L.} and Roberson, {Kirk B.} and Michiels, {Emma R.} and Kuhn, {Jessica E.} and Lopez, {Francisco A.} and Signorile, {Joseph F.}",
year = "2019",
month = "12",
doi = "10.1016/j.exger.2019.110740",
language = "English (US)",
volume = "128",
journal = "Experimental Gerontology",
issn = "0531-5565",
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TY - JOUR

T1 - Power vs strength training to improve muscular strength, power, balance and functional movement in individuals diagnosed with Parkinson's disease

AU - Cherup, Nicholas P.

AU - Buskard, Andrew N.L.

AU - Strand, Keri L.

AU - Roberson, Kirk B.

AU - Michiels, Emma R.

AU - Kuhn, Jessica E.

AU - Lopez, Francisco A.

AU - Signorile, Joseph F.

PY - 2019/12

Y1 - 2019/12

N2 - Background: Declines in strength and power are cardinal symptoms of Parkinson's disease (PD), a progressive neuromuscular disorder. Progressive resistance training (PRT) has been shown to reduce a wide variety of PD-related motor deficits; however, no study has examined differences between the two most common RT methodologies utilized in this population, high-load, low velocity strength training (ST) and low-load, high-velocity power training (PT). The primary purpose of this study was to compare the effects of ST and PT on measures of strength, power, balance and functional movement in persons with PD. Method: Thirty-five persons with mild to moderate PD (Hoehm and Yahr Stages = 1–3; UPDRS Part III = 30.6 ± 14.0) were randomized into either a ST or PT group involving 12 weeks of supervised PRT (2 visits per week). Leg press (LP) and chest press (CP) muscular strength (1RM) and muscular peak power (PP) were assessed before and after the twelve week training period as primary outcome measures. In addition, secondary measures of balance (Berg Balance Assessment (BBA), dynamic posturography (DMA), Modified Falls Efficacy Scale (MFES)), functional movement (timed up-and-go), and quality of life (PDQ-39 summary index and Mobility subscore) were obtained at the same time points, given the impact of PD symptoms on fall probability and independence. Results: Repeated measures ANCOVA revealed significant improvements in LP 1RM (Mdiff = 54.89 kg, 95% CI: 43.38, 66.40; p < .05; d = 3.38) and CP 1RM (Mdiff = 7.33 kg, 95% CI: 4.75, 9.91; p < .05; d = 2.02). Additionally, significant improvements were seen in LPPP (Mdiff = 112.27 W, 95% CI: 56.03, 168.51; p < .05; d = 1.42) and CPPP (Mdiff = 52.1 W, 95% CI: 23.38, 80.86; p = .001; d = 1.29). No significant improvements were seen for any secondary outcome measures, however BBA scores were shown to significantly decrease following the intervention (Mdiff = −1.686, 95% CI: −2.89, −0.482; p = .007 d = −0.96), although this change did not reach clinical significance (clinically meaningful change = ±4.0). In addition, the ST group demonstrated significantly poorer PDQ-39SI scores (Mdiff = 4.96, 95% CI: 0.54, 9.38; p = .029), whereas the entire sample showed significantly poorer PDQ-39MOB scores (Mdiff = 4.80, 95% CI: 0.17, 9.43; p = .043; d = 0.71). Conclusions: Both ST and PT appear to be effective at reducing the neuromuscular deficits associated with PD; however, the use of these interventions for improving functional performance was not supported.

AB - Background: Declines in strength and power are cardinal symptoms of Parkinson's disease (PD), a progressive neuromuscular disorder. Progressive resistance training (PRT) has been shown to reduce a wide variety of PD-related motor deficits; however, no study has examined differences between the two most common RT methodologies utilized in this population, high-load, low velocity strength training (ST) and low-load, high-velocity power training (PT). The primary purpose of this study was to compare the effects of ST and PT on measures of strength, power, balance and functional movement in persons with PD. Method: Thirty-five persons with mild to moderate PD (Hoehm and Yahr Stages = 1–3; UPDRS Part III = 30.6 ± 14.0) were randomized into either a ST or PT group involving 12 weeks of supervised PRT (2 visits per week). Leg press (LP) and chest press (CP) muscular strength (1RM) and muscular peak power (PP) were assessed before and after the twelve week training period as primary outcome measures. In addition, secondary measures of balance (Berg Balance Assessment (BBA), dynamic posturography (DMA), Modified Falls Efficacy Scale (MFES)), functional movement (timed up-and-go), and quality of life (PDQ-39 summary index and Mobility subscore) were obtained at the same time points, given the impact of PD symptoms on fall probability and independence. Results: Repeated measures ANCOVA revealed significant improvements in LP 1RM (Mdiff = 54.89 kg, 95% CI: 43.38, 66.40; p < .05; d = 3.38) and CP 1RM (Mdiff = 7.33 kg, 95% CI: 4.75, 9.91; p < .05; d = 2.02). Additionally, significant improvements were seen in LPPP (Mdiff = 112.27 W, 95% CI: 56.03, 168.51; p < .05; d = 1.42) and CPPP (Mdiff = 52.1 W, 95% CI: 23.38, 80.86; p = .001; d = 1.29). No significant improvements were seen for any secondary outcome measures, however BBA scores were shown to significantly decrease following the intervention (Mdiff = −1.686, 95% CI: −2.89, −0.482; p = .007 d = −0.96), although this change did not reach clinical significance (clinically meaningful change = ±4.0). In addition, the ST group demonstrated significantly poorer PDQ-39SI scores (Mdiff = 4.96, 95% CI: 0.54, 9.38; p = .029), whereas the entire sample showed significantly poorer PDQ-39MOB scores (Mdiff = 4.80, 95% CI: 0.17, 9.43; p = .043; d = 0.71). Conclusions: Both ST and PT appear to be effective at reducing the neuromuscular deficits associated with PD; however, the use of these interventions for improving functional performance was not supported.

KW - High-velocity training

KW - Neuromuscular function

KW - Pneumatic resistance

KW - Resistance training

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