Potential of intraluminal ultrasound for angioplasty guidance

Marwan Tabbara, George Kopchok, Rodney White

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The manifestation of atherosclerotic lesions in arteries can vary from asymptomatic thickening in the vessel wall to complete occlusion. Experimental studies on non-human primates1 and on human subjects2-4 indicate that atherosclerotic lesions may progress without a reduction in luminal diameter because of dilatation of the arterial wall. Although angiography has been considered the 'gold standard' for visualization of the arterial tree and detection of luminal narrowing, it does not demonstrate arterial wall thickening or morphology. Moreover, the measurement of luminal diameter of the same lesion can vary considerably depending on the plane of projection of the x-ray beam. This is attributed to the eccentric nature of the residual lumen in an atherosclerotic vessel.5 Extraluminal B-mode real time imaging has the feasibility of demonstrating arterial lumen and arterial wall thickness.6 However, it is still in some instances limited by inadequate resolution and image quality. Intraluminal ultrasound using a phased array or rotating transducer gives better definition of the vessel wall and luminal diameter as it is not limited by the tissue interposed between the vessel and the probe in transcutaneous devices. This paper demonstrates further experience with intravascular ultrasound as a diagnostic tool using B-mode real time imaging.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Int Soc for Optical Engineering
Number of pages4
ISBN (Print)0819402427, 9780819402424
StatePublished - Jan 1 1990
Externally publishedYes
EventProceedings of Optical Fibers in Medicine V - Los Angeles, CA, USA
Duration: Jan 14 1990Jan 19 1990

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


OtherProceedings of Optical Fibers in Medicine V
CityLos Angeles, CA, USA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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