Potential Impact of Targeted HIV Pre-Exposure Prophylaxis Uptake Among Male Sex Workers

William C. Goedel, Matthew J. Mimiaga, Maximilian R.F. King, Steven A. Safren, Kenneth H. Mayer, Philip A. Chan, Brandon D.L. Marshall, Katie B. Biello

Research output: Contribution to journalArticle

Abstract

Little is known about the potential population-level impact of HIV pre-exposure prophylaxis (PrEP) use among cisgender male sex workers (MSWs), a high-risk subset of cisgender men who have sex with men (MSM). Using an agent-based model, we simulated HIV transmission among cisgender MSM in Rhode Island to determine the impacts of PrEP implementation where cisgender MSWs were equally (“standard expansion”) or five times as likely (“focused expansion”) to initiate PrEP compared to other cisgender MSM. Without PrEP, the model predicted 920 new HIV infections over a decade, or an average incidence of 0.39 per 100 person-years. In a focused expansion scenario where 15% of at-risk cisgender MSM used PrEP, the total number of new HIV infections was reduced by 58.1% at a cost of $57,180 per quality-adjusted life-year (QALY) gained. Focused expansion of PrEP use among cisgender MSWs may be an efficient and cost-effective strategy for reducing HIV incidence in the broader population of cisgender MSM.

Original languageEnglish (US)
Article number5650
JournalScientific reports
Volume10
Issue number1
DOIs
StatePublished - Dec 1 2020

ASJC Scopus subject areas

  • General

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    Goedel, W. C., Mimiaga, M. J., King, M. R. F., Safren, S. A., Mayer, K. H., Chan, P. A., Marshall, B. D. L., & Biello, K. B. (2020). Potential Impact of Targeted HIV Pre-Exposure Prophylaxis Uptake Among Male Sex Workers. Scientific reports, 10(1), [5650]. https://doi.org/10.1038/s41598-020-62694-5