Postural stability in patients with Huntington's disease

Jun Ru Tian, Susan J. Herdman, David S. Zee, Susan E. Folstein

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

We characterized postural stability in patients with Huntington's disease (HD) by examining their ability to use different sensory cues to maintain balance and by recording their automatic postural responses to externally applied perturbations. Our HD patients, like normal subjects, depended more on proprioceptive than on visual cues to maintain balance. HD patients, however, developed more sway than normal subjects when proprioceptive cues, or when proprioceptive cues and vision, were altered. Thus, HD patients showed a defect in using vestibular information alone to maintain normal postural stability. The onset of compensatory motor responses in the lower extremities following sudden translations of the support surface was delayed by 30 to 60 msec in HD patients as compared with normal subjects. HD patients also had more sway and falls during unexpected rotations of the support surface, although they could appropriately reduce their motor responses on the next trial.

Original languageEnglish
Pages (from-to)1232-1238
Number of pages7
JournalNeurology
Volume42
Issue number6
StatePublished - Jun 1 1992

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Huntington Disease
Cues
Aptitude
Lower Extremity

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Tian, J. R., Herdman, S. J., Zee, D. S., & Folstein, S. E. (1992). Postural stability in patients with Huntington's disease. Neurology, 42(6), 1232-1238.

Postural stability in patients with Huntington's disease. / Tian, Jun Ru; Herdman, Susan J.; Zee, David S.; Folstein, Susan E.

In: Neurology, Vol. 42, No. 6, 01.06.1992, p. 1232-1238.

Research output: Contribution to journalArticle

Tian, JR, Herdman, SJ, Zee, DS & Folstein, SE 1992, 'Postural stability in patients with Huntington's disease', Neurology, vol. 42, no. 6, pp. 1232-1238.
Tian JR, Herdman SJ, Zee DS, Folstein SE. Postural stability in patients with Huntington's disease. Neurology. 1992 Jun 1;42(6):1232-1238.
Tian, Jun Ru ; Herdman, Susan J. ; Zee, David S. ; Folstein, Susan E. / Postural stability in patients with Huntington's disease. In: Neurology. 1992 ; Vol. 42, No. 6. pp. 1232-1238.
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