Posterior cyclodialysis cleft following intravitreal injection

Rachel H. Lee, Aubrey R. Tirpack, Janet L. Davis, Mohamed S. Sayed, Vikas Chopra, Steven J. Gedde

Research output: Contribution to journalArticlepeer-review


Purpose: To describe an unusual complication of an intravitreal injection. Observation: Here, we report a case of hypotony following an intravitreal injection due to a posterior cyclodialysis cleft and describe its management and resolution. Conclusions: Posterior cyclodialysis clefts are a rare cause of hypotony following intravitreal injection. Posterior clefts may not be visualized by conventional gonioscopy. Ultrasound biomicroscopy may be useful in aiding diagnosis. Importance: This report highlights a rare cause of hypotony following intravitreal injection and illustrates the importance of adjunctive imaging for accurate diagnosis.

Original languageEnglish (US)
Article number101134
JournalAmerican Journal of Ophthalmology Case Reports
StatePublished - Sep 2021


  • Complications of intravitreal injections
  • Cyclodialysis cleft
  • Hypotony

ASJC Scopus subject areas

  • Ophthalmology


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