Abstract
Purpose of Review: This article seeks to review the current literature on post-burn pruritus and its treatments, as well as to propose new treatments that may be of potential benefit for these patients. Recent Findings: Post-burn pruritus has been reported to affect as many as 93% of patients after a burn injury. Pruritus is extremely distressing to these patients, yet the current state of treatment, mostly antihistamines and emollients, is still widely ineffective in providing relief of itch. Summary: Therapies that are effective in treating pruritus and that may act as superior treatment options for patients suffering from post-burn pruritus include gabapentin and pregabalin, topical ketamine-lidocaine-amitriptyline, opioid medications, neurokinin-1 inhibitors, antidepressants, anti-cytokines, PAR-2 inhibitors, and botulinum toxin among others.
Original language | English (US) |
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Pages (from-to) | 90-98 |
Number of pages | 9 |
Journal | Current Trauma Reports |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Jun 15 2019 |
Keywords
- Burn injury
- Burn scar
- Itch
- Post-burn itch
- Post-burn pruritus
- Pruritus
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
- Rehabilitation