Abstract
The use of protease Inhibitors (PI) has been associated with many adverse effects including increased tendency to bleed, which is particularly problematic in individuals with congenital coagulation disorders. We report the occurrence of spontaneous intracranial bleeding in an human immunodeficiency virus (HIV)-infected adolescent with hemophilia A who was receiving amprenavir (APV). The bleeding resolved on discontinuation of APV. This case report highlights a need for awareness of increased bleeding as a potentially serious complication associated with the use of all currently licensed PIs in individuals with hemophilia.
| Original language | English |
|---|---|
| Pages (from-to) | 347-352 |
| Number of pages | 6 |
| Journal | AIDS Patient Care and STDs |
| Volume | 15 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 30 2001 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Leadership and Management
- Nursing(all)
Cite this
Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac. / Kodoth, S.; Bakshi, S.; Scimeca, P.; Black, K.; Pahwa, Savita G.
In: AIDS Patient Care and STDs, Vol. 15, No. 7, 30.07.2001, p. 347-352.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac
AU - Kodoth, S.
AU - Bakshi, S.
AU - Scimeca, P.
AU - Black, K.
AU - Pahwa, Savita G
PY - 2001/7/30
Y1 - 2001/7/30
N2 - The use of protease Inhibitors (PI) has been associated with many adverse effects including increased tendency to bleed, which is particularly problematic in individuals with congenital coagulation disorders. We report the occurrence of spontaneous intracranial bleeding in an human immunodeficiency virus (HIV)-infected adolescent with hemophilia A who was receiving amprenavir (APV). The bleeding resolved on discontinuation of APV. This case report highlights a need for awareness of increased bleeding as a potentially serious complication associated with the use of all currently licensed PIs in individuals with hemophilia.
AB - The use of protease Inhibitors (PI) has been associated with many adverse effects including increased tendency to bleed, which is particularly problematic in individuals with congenital coagulation disorders. We report the occurrence of spontaneous intracranial bleeding in an human immunodeficiency virus (HIV)-infected adolescent with hemophilia A who was receiving amprenavir (APV). The bleeding resolved on discontinuation of APV. This case report highlights a need for awareness of increased bleeding as a potentially serious complication associated with the use of all currently licensed PIs in individuals with hemophilia.
UR - http://www.scopus.com/inward/record.url?scp=0034945077&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034945077&partnerID=8YFLogxK
U2 - 10.1089/108729101750301898
DO - 10.1089/108729101750301898
M3 - Article
C2 - 11483161
AN - SCOPUS:0034945077
VL - 15
SP - 347
EP - 352
JO - AIDS Patient Care and STDs
JF - AIDS Patient Care and STDs
SN - 1087-2914
IS - 7
ER -