Abstract
The use of protease Inhibitors (PI) has been associated with many adverse effects including increased tendency to bleed, which is particularly problematic in individuals with congenital coagulation disorders. We report the occurrence of spontaneous intracranial bleeding in an human immunodeficiency virus (HIV)-infected adolescent with hemophilia A who was receiving amprenavir (APV). The bleeding resolved on discontinuation of APV. This case report highlights a need for awareness of increased bleeding as a potentially serious complication associated with the use of all currently licensed PIs in individuals with hemophilia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 347-352 |
| Number of pages | 6 |
| Journal | AIDS patient care and STDs |
| Volume | 15 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 30 2001 |
| Externally published | Yes |
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Infectious Diseases
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Kodoth, S., Bakshi, S., Scimeca, P., Black, K., & Pahwa, S. (2001). Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac. AIDS patient care and STDs, 15(7), 347-352. https://doi.org/10.1089/108729101750301898