Abstract
Background: Improving mental and physical health of patients with implantable cardioverter defibrillators (ICD) is critical because this group is at high risk for ventricular arrhythmias and sudden death and depressed or anxious cardiovascular disease (CVD) patients appear to be at even higher risk for mortality compared to nondepressed or nonanxious CVD patients. Further, autonomic dysfunction is present in these patients, and negative emotions and arrhythmias form a downward spiral further worsening mood, well-being, and cardiovascular health. Much research demonstrates that positive emotion is related to health benefits, improved physiology, and increased survival. Methods and Results: This is a two-arm randomized controlled trial aiming to recruit 60 adult ICD patients comparing 12 individually delivered, weekly sessions of: (1) a positive emotion-focused cognitive-behavioral therapy (Quality of Life Therapy [QOLT]), and (2) Heart Healthy Education. Autonomic functioning, heart rhythm indices, and psychosocial health are measured at baseline, 3 months, and 9 months. The first goal is feasibility and acceptability, with the primary outcome being arrhythmic event frequency data. Conclusion: This study is designed to test whether QOLT produces changes in mood, quality of life/well-being, autonomic function, and arrhythmic and ICD therapy event rates. This feasibility trial is a foundational step for the next trial of QOLT to help determine whether a 3-month QOLT trial can reduce arrhythmias occurrences among ICD patients, and examine a mechanism of autonomic functioning. This study may help to develop and implement new medical or psychological therapies for ICD patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 458-470 |
| Number of pages | 13 |
| Journal | PACE - Pacing and Clinical Electrophysiology |
| Volume | 39 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 2016 |
| Externally published | Yes |
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Keywords
- autonomic function
- behavioral medicine
- implantable cardioverter defibrillator (ICD)
- positive emotion
- psychological treatment
- quality of life
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Positive Psychotherapy to Improve Autonomic Function and Mood in ICD Patients (PAM-ICD) : Rationale and Design of an RCT Currently Underway. / Serber, Eva R.; Fava, Joseph L.; Christon, Lillian M.; Buxton, Alfred E.; Goldberger, Jeffrey; Gold, Michael R.; Rodrigue, James R.; Frisch, Michael B.
In: PACE - Pacing and Clinical Electrophysiology, Vol. 39, No. 5, 01.01.2016, p. 458-470.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Positive Psychotherapy to Improve Autonomic Function and Mood in ICD Patients (PAM-ICD)
T2 - Rationale and Design of an RCT Currently Underway
AU - Serber, Eva R.
AU - Fava, Joseph L.
AU - Christon, Lillian M.
AU - Buxton, Alfred E.
AU - Goldberger, Jeffrey
AU - Gold, Michael R.
AU - Rodrigue, James R.
AU - Frisch, Michael B.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Background: Improving mental and physical health of patients with implantable cardioverter defibrillators (ICD) is critical because this group is at high risk for ventricular arrhythmias and sudden death and depressed or anxious cardiovascular disease (CVD) patients appear to be at even higher risk for mortality compared to nondepressed or nonanxious CVD patients. Further, autonomic dysfunction is present in these patients, and negative emotions and arrhythmias form a downward spiral further worsening mood, well-being, and cardiovascular health. Much research demonstrates that positive emotion is related to health benefits, improved physiology, and increased survival. Methods and Results: This is a two-arm randomized controlled trial aiming to recruit 60 adult ICD patients comparing 12 individually delivered, weekly sessions of: (1) a positive emotion-focused cognitive-behavioral therapy (Quality of Life Therapy [QOLT]), and (2) Heart Healthy Education. Autonomic functioning, heart rhythm indices, and psychosocial health are measured at baseline, 3 months, and 9 months. The first goal is feasibility and acceptability, with the primary outcome being arrhythmic event frequency data. Conclusion: This study is designed to test whether QOLT produces changes in mood, quality of life/well-being, autonomic function, and arrhythmic and ICD therapy event rates. This feasibility trial is a foundational step for the next trial of QOLT to help determine whether a 3-month QOLT trial can reduce arrhythmias occurrences among ICD patients, and examine a mechanism of autonomic functioning. This study may help to develop and implement new medical or psychological therapies for ICD patients.
AB - Background: Improving mental and physical health of patients with implantable cardioverter defibrillators (ICD) is critical because this group is at high risk for ventricular arrhythmias and sudden death and depressed or anxious cardiovascular disease (CVD) patients appear to be at even higher risk for mortality compared to nondepressed or nonanxious CVD patients. Further, autonomic dysfunction is present in these patients, and negative emotions and arrhythmias form a downward spiral further worsening mood, well-being, and cardiovascular health. Much research demonstrates that positive emotion is related to health benefits, improved physiology, and increased survival. Methods and Results: This is a two-arm randomized controlled trial aiming to recruit 60 adult ICD patients comparing 12 individually delivered, weekly sessions of: (1) a positive emotion-focused cognitive-behavioral therapy (Quality of Life Therapy [QOLT]), and (2) Heart Healthy Education. Autonomic functioning, heart rhythm indices, and psychosocial health are measured at baseline, 3 months, and 9 months. The first goal is feasibility and acceptability, with the primary outcome being arrhythmic event frequency data. Conclusion: This study is designed to test whether QOLT produces changes in mood, quality of life/well-being, autonomic function, and arrhythmic and ICD therapy event rates. This feasibility trial is a foundational step for the next trial of QOLT to help determine whether a 3-month QOLT trial can reduce arrhythmias occurrences among ICD patients, and examine a mechanism of autonomic functioning. This study may help to develop and implement new medical or psychological therapies for ICD patients.
KW - autonomic function
KW - behavioral medicine
KW - implantable cardioverter defibrillator (ICD)
KW - positive emotion
KW - psychological treatment
KW - quality of life
UR - http://www.scopus.com/inward/record.url?scp=84959387186&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959387186&partnerID=8YFLogxK
U2 - 10.1111/pace.12820
DO - 10.1111/pace.12820
M3 - Article
C2 - 26813033
AN - SCOPUS:84959387186
VL - 39
SP - 458
EP - 470
JO - PACE - Pacing and Clinical Electrophysiology
JF - PACE - Pacing and Clinical Electrophysiology
SN - 0147-8389
IS - 5
ER -