Positive Psychotherapy to Improve Autonomic Function and Mood in ICD Patients (PAM-ICD): Rationale and Design of an RCT Currently Underway

Eva R. Serber, Joseph L. Fava, Lillian M. Christon, Alfred E. Buxton, Jeffrey Goldberger, Michael R. Gold, James R. Rodrigue, Michael B. Frisch

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Improving mental and physical health of patients with implantable cardioverter defibrillators (ICD) is critical because this group is at high risk for ventricular arrhythmias and sudden death and depressed or anxious cardiovascular disease (CVD) patients appear to be at even higher risk for mortality compared to nondepressed or nonanxious CVD patients. Further, autonomic dysfunction is present in these patients, and negative emotions and arrhythmias form a downward spiral further worsening mood, well-being, and cardiovascular health. Much research demonstrates that positive emotion is related to health benefits, improved physiology, and increased survival. Methods and Results: This is a two-arm randomized controlled trial aiming to recruit 60 adult ICD patients comparing 12 individually delivered, weekly sessions of: (1) a positive emotion-focused cognitive-behavioral therapy (Quality of Life Therapy [QOLT]), and (2) Heart Healthy Education. Autonomic functioning, heart rhythm indices, and psychosocial health are measured at baseline, 3 months, and 9 months. The first goal is feasibility and acceptability, with the primary outcome being arrhythmic event frequency data. Conclusion: This study is designed to test whether QOLT produces changes in mood, quality of life/well-being, autonomic function, and arrhythmic and ICD therapy event rates. This feasibility trial is a foundational step for the next trial of QOLT to help determine whether a 3-month QOLT trial can reduce arrhythmias occurrences among ICD patients, and examine a mechanism of autonomic functioning. This study may help to develop and implement new medical or psychological therapies for ICD patients.

Original languageEnglish (US)
Pages (from-to)458-470
Number of pages13
JournalPACE - Pacing and Clinical Electrophysiology
Volume39
Issue number5
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Implantable Defibrillators
Psychotherapy
Quality of Life
Cardiac Arrhythmias
Emotions
Cardiovascular Diseases
Therapeutics
Health
Cognitive Therapy
Insurance Benefits
Sudden Death
Mental Health
Randomized Controlled Trials
Psychology
Education
Survival
Mortality
Research

Keywords

  • autonomic function
  • behavioral medicine
  • implantable cardioverter defibrillator (ICD)
  • positive emotion
  • psychological treatment
  • quality of life

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Positive Psychotherapy to Improve Autonomic Function and Mood in ICD Patients (PAM-ICD) : Rationale and Design of an RCT Currently Underway. / Serber, Eva R.; Fava, Joseph L.; Christon, Lillian M.; Buxton, Alfred E.; Goldberger, Jeffrey; Gold, Michael R.; Rodrigue, James R.; Frisch, Michael B.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 39, No. 5, 01.01.2016, p. 458-470.

Research output: Contribution to journalArticle

Serber, Eva R. ; Fava, Joseph L. ; Christon, Lillian M. ; Buxton, Alfred E. ; Goldberger, Jeffrey ; Gold, Michael R. ; Rodrigue, James R. ; Frisch, Michael B. / Positive Psychotherapy to Improve Autonomic Function and Mood in ICD Patients (PAM-ICD) : Rationale and Design of an RCT Currently Underway. In: PACE - Pacing and Clinical Electrophysiology. 2016 ; Vol. 39, No. 5. pp. 458-470.
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