Population structure of Anopheles gambiae along the Kenyan coast

Janet T. Midega, Ephantus J. Muturi, Frederick N. Baliraine, Charles M. Mbogo, John Githure, John C Beier, Guiyun Yan

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In the tropics, Anopheles mosquito abundance is greatest during the wet season and decline significantly during the dry season as larval habitats shrink. Population size fluctuations between wet and dry seasons may lead to variation in distribution of specific alleles within natural Anopheles populations, and a possible effect on the population genetic structure. We used 11 microsatellite markers to examine the effect of seasonality on population genetic structure of Anopheles gambiae s.s. at two sites along the Kenyan coast. All loci were highly polymorphic with the total number of alleles for pooled samples ranging from 7 (locus ND36) to 21 (locus AG2H46). Significant estimates of genetic differentiation between sites and seasons were observed suggesting the existence of spatio-temporal subpopulation structuring. Genetic bottleneck analysis showed no indication of excess heterozygosity in any of the populations. These findings suggest that along the Kenyan coast, seasonality and site specific ecological factors can alter the genetic structure of A. gambiae s.s. populations.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalActa Tropica
Volume114
Issue number2
DOIs
StatePublished - May 1 2010

Fingerprint

Anopheles gambiae
Genetic Structures
population structure
Anopheles
coasts
loci
population genetics
dry season
wet season
Population Genetics
Population
alleles
Alleles
genetic techniques and protocols
tropics
heterozygosity
Culicidae
population size
Population Density
microsatellite repeats

Keywords

  • Anopheles gambiae
  • Kenyan coast
  • Population structure
  • Seasonality

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Midega, J. T., Muturi, E. J., Baliraine, F. N., Mbogo, C. M., Githure, J., Beier, J. C., & Yan, G. (2010). Population structure of Anopheles gambiae along the Kenyan coast. Acta Tropica, 114(2), 103-108. https://doi.org/10.1016/j.actatropica.2010.01.011

Population structure of Anopheles gambiae along the Kenyan coast. / Midega, Janet T.; Muturi, Ephantus J.; Baliraine, Frederick N.; Mbogo, Charles M.; Githure, John; Beier, John C; Yan, Guiyun.

In: Acta Tropica, Vol. 114, No. 2, 01.05.2010, p. 103-108.

Research output: Contribution to journalArticle

Midega, JT, Muturi, EJ, Baliraine, FN, Mbogo, CM, Githure, J, Beier, JC & Yan, G 2010, 'Population structure of Anopheles gambiae along the Kenyan coast', Acta Tropica, vol. 114, no. 2, pp. 103-108. https://doi.org/10.1016/j.actatropica.2010.01.011
Midega JT, Muturi EJ, Baliraine FN, Mbogo CM, Githure J, Beier JC et al. Population structure of Anopheles gambiae along the Kenyan coast. Acta Tropica. 2010 May 1;114(2):103-108. https://doi.org/10.1016/j.actatropica.2010.01.011
Midega, Janet T. ; Muturi, Ephantus J. ; Baliraine, Frederick N. ; Mbogo, Charles M. ; Githure, John ; Beier, John C ; Yan, Guiyun. / Population structure of Anopheles gambiae along the Kenyan coast. In: Acta Tropica. 2010 ; Vol. 114, No. 2. pp. 103-108.
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