Population-Derived Comparisons of Ambulatory and Office Blood Pressures: Implications for the Determination of Usual Blood Pressure and the Concept of White Coat Hypertension

Kevin A. Pearce, Richard H. Grimm, Jonnagadda S Rao, Kenneth Svendsen, Philip R. Liebson, James D. Neaton, Kristine Ensrud

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Background.—Ambulatory blood pressures (BPs) have generally been reported to be lower than office blood pressures, but population-based data are lacking. Methods.—To better characterize ambulatory and office BP relationships, we explored the interrelationships of BPs measured in the office by mercury sphygmomanometry, 24-hour ambulatory BP measured with a portable device, and echocardiographic left ventricular mass in a random sample of 50 men aged 51 to 72 years drawn from a much larger pool. Office BP was based on the mean of 10 measurements performed over five visits. Results.—Among all participants, mean 24-hour ambulatory and mean office BPs were highly correlated: r (systolic/ diastolic) =.90/.79; and both mean 24-hour and mean awake ambulatory BPs were significantly higher than mean office BPs. For the subsample not receiving antihypertensive therapy, mean ambulatory and office BPs were similar in terms of their associations with Penn left ventricular mass index (LVMI). No association between BP and left ventricular mass was observed among the subjects receiving antihypertensive medication. Conclusions.—We conclude that a single session of 24-hour ambulatory BP monitoring is unlikely to improve the determination of usual BP in older white men beyond that achievable with BP carefully measured over five separate office visits; and that white coat hypertension is rare in this population.

Original languageEnglish (US)
Pages (from-to)750-756
Number of pages7
JournalArchives of Internal Medicine
Volume152
Issue number4
DOIs
StatePublished - 1992
Externally publishedYes

Fingerprint

Blood Pressure Determination
White Coat Hypertension
Blood Pressure
Population
Antihypertensive Agents
Office Visits
Ambulatory Blood Pressure Monitoring
Mercury

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Population-Derived Comparisons of Ambulatory and Office Blood Pressures : Implications for the Determination of Usual Blood Pressure and the Concept of White Coat Hypertension. / Pearce, Kevin A.; Grimm, Richard H.; Rao, Jonnagadda S; Svendsen, Kenneth; Liebson, Philip R.; Neaton, James D.; Ensrud, Kristine.

In: Archives of Internal Medicine, Vol. 152, No. 4, 1992, p. 750-756.

Research output: Contribution to journalArticle

Pearce, Kevin A. ; Grimm, Richard H. ; Rao, Jonnagadda S ; Svendsen, Kenneth ; Liebson, Philip R. ; Neaton, James D. ; Ensrud, Kristine. / Population-Derived Comparisons of Ambulatory and Office Blood Pressures : Implications for the Determination of Usual Blood Pressure and the Concept of White Coat Hypertension. In: Archives of Internal Medicine. 1992 ; Vol. 152, No. 4. pp. 750-756.
@article{5654d17dccdd436d9ee7e2e52d1b1546,
title = "Population-Derived Comparisons of Ambulatory and Office Blood Pressures: Implications for the Determination of Usual Blood Pressure and the Concept of White Coat Hypertension",
abstract = "Background.—Ambulatory blood pressures (BPs) have generally been reported to be lower than office blood pressures, but population-based data are lacking. Methods.—To better characterize ambulatory and office BP relationships, we explored the interrelationships of BPs measured in the office by mercury sphygmomanometry, 24-hour ambulatory BP measured with a portable device, and echocardiographic left ventricular mass in a random sample of 50 men aged 51 to 72 years drawn from a much larger pool. Office BP was based on the mean of 10 measurements performed over five visits. Results.—Among all participants, mean 24-hour ambulatory and mean office BPs were highly correlated: r (systolic/ diastolic) =.90/.79; and both mean 24-hour and mean awake ambulatory BPs were significantly higher than mean office BPs. For the subsample not receiving antihypertensive therapy, mean ambulatory and office BPs were similar in terms of their associations with Penn left ventricular mass index (LVMI). No association between BP and left ventricular mass was observed among the subjects receiving antihypertensive medication. Conclusions.—We conclude that a single session of 24-hour ambulatory BP monitoring is unlikely to improve the determination of usual BP in older white men beyond that achievable with BP carefully measured over five separate office visits; and that white coat hypertension is rare in this population.",
author = "Pearce, {Kevin A.} and Grimm, {Richard H.} and Rao, {Jonnagadda S} and Kenneth Svendsen and Liebson, {Philip R.} and Neaton, {James D.} and Kristine Ensrud",
year = "1992",
doi = "10.1001/archinte.1992.00400160062012",
language = "English (US)",
volume = "152",
pages = "750--756",
journal = "JAMA Internal Medicine",
issn = "2168-6106",
publisher = "American Medical Association",
number = "4",

}

TY - JOUR

T1 - Population-Derived Comparisons of Ambulatory and Office Blood Pressures

T2 - Implications for the Determination of Usual Blood Pressure and the Concept of White Coat Hypertension

AU - Pearce, Kevin A.

AU - Grimm, Richard H.

AU - Rao, Jonnagadda S

AU - Svendsen, Kenneth

AU - Liebson, Philip R.

AU - Neaton, James D.

AU - Ensrud, Kristine

PY - 1992

Y1 - 1992

N2 - Background.—Ambulatory blood pressures (BPs) have generally been reported to be lower than office blood pressures, but population-based data are lacking. Methods.—To better characterize ambulatory and office BP relationships, we explored the interrelationships of BPs measured in the office by mercury sphygmomanometry, 24-hour ambulatory BP measured with a portable device, and echocardiographic left ventricular mass in a random sample of 50 men aged 51 to 72 years drawn from a much larger pool. Office BP was based on the mean of 10 measurements performed over five visits. Results.—Among all participants, mean 24-hour ambulatory and mean office BPs were highly correlated: r (systolic/ diastolic) =.90/.79; and both mean 24-hour and mean awake ambulatory BPs were significantly higher than mean office BPs. For the subsample not receiving antihypertensive therapy, mean ambulatory and office BPs were similar in terms of their associations with Penn left ventricular mass index (LVMI). No association between BP and left ventricular mass was observed among the subjects receiving antihypertensive medication. Conclusions.—We conclude that a single session of 24-hour ambulatory BP monitoring is unlikely to improve the determination of usual BP in older white men beyond that achievable with BP carefully measured over five separate office visits; and that white coat hypertension is rare in this population.

AB - Background.—Ambulatory blood pressures (BPs) have generally been reported to be lower than office blood pressures, but population-based data are lacking. Methods.—To better characterize ambulatory and office BP relationships, we explored the interrelationships of BPs measured in the office by mercury sphygmomanometry, 24-hour ambulatory BP measured with a portable device, and echocardiographic left ventricular mass in a random sample of 50 men aged 51 to 72 years drawn from a much larger pool. Office BP was based on the mean of 10 measurements performed over five visits. Results.—Among all participants, mean 24-hour ambulatory and mean office BPs were highly correlated: r (systolic/ diastolic) =.90/.79; and both mean 24-hour and mean awake ambulatory BPs were significantly higher than mean office BPs. For the subsample not receiving antihypertensive therapy, mean ambulatory and office BPs were similar in terms of their associations with Penn left ventricular mass index (LVMI). No association between BP and left ventricular mass was observed among the subjects receiving antihypertensive medication. Conclusions.—We conclude that a single session of 24-hour ambulatory BP monitoring is unlikely to improve the determination of usual BP in older white men beyond that achievable with BP carefully measured over five separate office visits; and that white coat hypertension is rare in this population.

UR - http://www.scopus.com/inward/record.url?scp=0026582748&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026582748&partnerID=8YFLogxK

U2 - 10.1001/archinte.1992.00400160062012

DO - 10.1001/archinte.1992.00400160062012

M3 - Article

C2 - 1558432

AN - SCOPUS:0026582748

VL - 152

SP - 750

EP - 756

JO - JAMA Internal Medicine

JF - JAMA Internal Medicine

SN - 2168-6106

IS - 4

ER -