Polyglyconate fixation successfully stabilizes zygomatic osteotomies in a nonhuman primate

Seth Thaller, T. Lee, H. Tesluk

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Investigators have reported problems with metal plates and screws, including restriction of craniofacial growth necessitating secondary removal; bone resorption secondary to stress shielding; increased incidence of infection, extrusion, and palpability, especially in regions with minimal soft-tissue coverage; and interference with radiological studies and postoperative radiation therapy. Biodegradable rigid fixation can easily eliminate a majority of these problems because the material provides adequate fixation for a finite interval corresponding to bony repair. For this reason, there has been increasing interest in developing satisfactory biodegradable plate and screw systems. We tested a commercially developed polyglyconate plate and screw system to stabilize zygomatic osteotomies in a nonhuman primate model before embarking on clinical trials. In this experimental model, the stabilized segments revealed satisfactory alignment; in the control animals, the bony fragments became significantly displaced. This polyglyconate plate and screw system appears to have a promising role in the surgical correction of craniomaxillofacial deformities in humans, and clinical testing should commence.

Original languageEnglish
Pages (from-to)459-464
Number of pages6
JournalJournal of Craniofacial Surgery
Volume6
Issue number6
StatePublished - Jan 1 1995

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Osteotomy
Primates
Bone Resorption
Theoretical Models
Radiotherapy
Metals
Research Personnel
Clinical Trials
Incidence
Growth
Infection
polyglyconate

Keywords

  • Biodegradable plates and screws
  • Polyglyconate
  • Zygomatic osteotomies

ASJC Scopus subject areas

  • Surgery

Cite this

Polyglyconate fixation successfully stabilizes zygomatic osteotomies in a nonhuman primate. / Thaller, Seth; Lee, T.; Tesluk, H.

In: Journal of Craniofacial Surgery, Vol. 6, No. 6, 01.01.1995, p. 459-464.

Research output: Contribution to journalArticle

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