Abstract
Two patients receiving oral etoposide therapy developed Pneumocystis jirovecii pneumonia during chemotherapy with significant lymphopenia without corticosteroid use. In this commentary we discuss cellular mechanisms by which etoposide induced CD4+ T lymphocyte dysfunction and reduced survival may lead to predisposition to P. jirovecii infection.
Original language | English (US) |
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Article number | e242485 |
Journal | BMJ case reports |
Volume | 14 |
Issue number | 6 |
DOIs | |
State | Published - Jun 10 2021 |
Keywords
- haematology (incl blood transfusion)
- infections
- malignant disease and immunosuppression
- pneumonia (infectious disease)
ASJC Scopus subject areas
- Medicine(all)