Plasma somatomedin‐C levels in systemic sclerosis

M. J. ROTHE; R. D. ALTMAN; V. FALANGA

doi:10.1111/j.1365-2133.1988.tb03476.x

Plasma somatomedin‐C levels in systemic sclerosis

M. J. ROTHE, R. D. ALTMAN, V. FALANGA

Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We have measured the plasma levels of somatomedin‐C (SM‐C) or insulin‐like growth factor I (IGF‐I) in 13 patients with progressive systemic sclerosis (PSS) and age and sex matched healthy controls. We found the plasma SM‐C levels to be within normal limits in all the patients. Thus, if somatomedin‐C plays a role in the pathogenesis of PSS, it is more likely to be at the fibroblast receptor level or in the synthetic response of fibroblasts to SM‐C.

Original language	English (US)
Pages (from-to)	639-642
Number of pages	4
Journal	British Journal of Dermatology
Volume	119
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2133.1988.tb03476.x
State	Published - Nov 1988

ASJC Scopus subject areas

Dermatology

Access to Document

10.1111/j.1365-2133.1988.tb03476.x

Fingerprint Dive into the research topics of 'Plasma somatomedin‐C levels in systemic sclerosis'. Together they form a unique fingerprint.

Cite this

@article{7362bbda1f4f480d8f373087aba835ed,

title = "Plasma somatomedin‐C levels in systemic sclerosis",

abstract = "We have measured the plasma levels of somatomedin‐C (SM‐C) or insulin‐like growth factor I (IGF‐I) in 13 patients with progressive systemic sclerosis (PSS) and age and sex matched healthy controls. We found the plasma SM‐C levels to be within normal limits in all the patients. Thus, if somatomedin‐C plays a role in the pathogenesis of PSS, it is more likely to be at the fibroblast receptor level or in the synthetic response of fibroblasts to SM‐C.",

author = "ROTHE, {M. J.} and ALTMAN, {R. D.} and V. FALANGA",

year = "1988",

month = nov,

doi = "10.1111/j.1365-2133.1988.tb03476.x",

language = "English (US)",

volume = "119",

pages = "639--642",

journal = "British Journal of Dermatology",

issn = "0007-0963",

publisher = "Wiley-Blackwell",

number = "5",

}

TY - JOUR

T1 - Plasma somatomedin‐C levels in systemic sclerosis

AU - ROTHE, M. J.

AU - ALTMAN, R. D.

AU - FALANGA, V.

PY - 1988/11

Y1 - 1988/11

N2 - We have measured the plasma levels of somatomedin‐C (SM‐C) or insulin‐like growth factor I (IGF‐I) in 13 patients with progressive systemic sclerosis (PSS) and age and sex matched healthy controls. We found the plasma SM‐C levels to be within normal limits in all the patients. Thus, if somatomedin‐C plays a role in the pathogenesis of PSS, it is more likely to be at the fibroblast receptor level or in the synthetic response of fibroblasts to SM‐C.

AB - We have measured the plasma levels of somatomedin‐C (SM‐C) or insulin‐like growth factor I (IGF‐I) in 13 patients with progressive systemic sclerosis (PSS) and age and sex matched healthy controls. We found the plasma SM‐C levels to be within normal limits in all the patients. Thus, if somatomedin‐C plays a role in the pathogenesis of PSS, it is more likely to be at the fibroblast receptor level or in the synthetic response of fibroblasts to SM‐C.

UR - http://www.scopus.com/inward/record.url?scp=0023692513&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023692513&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2133.1988.tb03476.x

DO - 10.1111/j.1365-2133.1988.tb03476.x

M3 - Article

C2 - 3207616

AN - SCOPUS:0023692513

VL - 119

SP - 639

EP - 642

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

IS - 5

ER -

Plasma somatomedin‐C levels in systemic sclerosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this