Abstract
In this open-label, randomized, multiple-dose, two-treatment crossover study, 24 postmenopausal women with moderate to severe atrophic vaginitis received 0.3 mg conjugated estrogens daily for 14 days: 7 days orally (0.3 mg tablet) and 7 days vaginally (0.5 g cream). Steady-state plasma concentrations of E2 and estrone were one-third lower after vaginal versus oral administration of conjugated estrogens.
Original language | English (US) |
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Pages (from-to) | 2365-2368 |
Number of pages | 4 |
Journal | Fertility and sterility |
Volume | 94 |
Issue number | 6 |
DOIs | |
State | Published - Nov 1 2010 |
Keywords
- absorption
- Conjugated estrogens
- ET
- pharmacokinetics
- vaginal cream
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Reproductive Medicine