Plasma electrophoretic profiles in the eastern massasauga (sistrurus catenatus) and influences of age, sex, year, location, and snake fungal disease

Matthew C. Allender, Randall E. Junge, Sarah Baker-Wylie, Eric T. Hileman, Lisa J. Faust, Carolyn Cray

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The purpose of this study was to establish reference intervals of the protein electrophoretic fractions and the acute-phase proteins hemoglobin binding protein (as determined by the haptoglobin assay) and C-reactive protein (CRP) and assess any possible correlations between varying age class, sex, location (Illinois or Michigan), year, or presence of snake fungal disease (SFD). Banked plasma samples were assayed from 130 eastern massasaugas from 2009 to 2014 in Illinois and Michigan. Snakes from Michigan had higher total protein (mean: 5.50 g/dl), albumin/globulin ratio (0.42), albumin (1.59 g/dl), and gamma globulins (0.55 g/dl) than from snakes in Illinois (4.72 g/dl, 0.29, 1.03 g/dl, 0.38 g/dl, respectively). Snakes in Illinois (22.19 g/ml) had higher CRP than snakes in Michigan (10.89 mg/ml). Adults had higher gamma globulins (0.47 g/dl) than juveniles (0.28 g/dl). Males had higher alpha-2 globulins (0.98 g/dl) and CRP (21.4 mg/ml) than females (0.85, 11.6, respectively). There were no significant differences in absolute plasma proteins in SFD-positive snakes, but the percentage of gamma globulins was significantly higher in positive snakes. Future research in this area can now build on this data to determine changes in population health over time or due to specific environmental or disease threats.

Original languageEnglish (US)
Pages (from-to)767-773
Number of pages7
JournalJournal of Zoo and Wildlife Medicine
Volume46
Issue number4
DOIs
StatePublished - Dec 1 2015

Keywords

  • Acute-phase proteins
  • C-reactive protein
  • electrophoresis
  • haptoglobin
  • reptile
  • serum amyloid A.

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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