Abstract
In 42 low-birth-weight infants (<1,200 gm), we have compared the effects of intravenous nutrition supplement versus conventional feedings on growth, morbidity, mortality, and plasma amino acid patterns. Despite similar total caloric intake in INS and control groups, weight gain was greater in the INS infants. The overall mortality rate did not differ in the two groups. Nonsurviving infants receiving INS lived longer (mean=30 days) than nonsurviving CON infants (mean=5 days). Complications were equally frequent in both group except that hyperglycemia occurred more often in infants receiving INS. The plasma aminogram of the LBW infant is described and compared to those of the full-term infant and adult. Hypoaminoacidemia was present at birth in the LBW infants, concentrations of glutamine, alanine, glycine, histidine, and ornithine being significantly (P<0.05) below FT values. During INS, elevations of threonine, serine, and methionine above FT values occurred. Glutamine remained subnormal despite INS. Recommendations for an INS solution more suitable for use in LBW infants are presented.
| Original language | English |
|---|---|
| Pages (from-to) | 766-772 |
| Number of pages | 7 |
| Journal | The Journal of pediatrics |
| Volume | 86 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1975 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Plasma amino acid patterns during supplemental intravenous nutrition of low-birth-weight infants. / Abitbol, Carolyn; Feldman, Donita B.; Ahmann, Peter; Rudman, Daniel.
In: The Journal of pediatrics, Vol. 86, No. 5, 01.01.1975, p. 766-772.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasma amino acid patterns during supplemental intravenous nutrition of low-birth-weight infants
AU - Abitbol, Carolyn
AU - Feldman, Donita B.
AU - Ahmann, Peter
AU - Rudman, Daniel
PY - 1975/1/1
Y1 - 1975/1/1
N2 - In 42 low-birth-weight infants (<1,200 gm), we have compared the effects of intravenous nutrition supplement versus conventional feedings on growth, morbidity, mortality, and plasma amino acid patterns. Despite similar total caloric intake in INS and control groups, weight gain was greater in the INS infants. The overall mortality rate did not differ in the two groups. Nonsurviving infants receiving INS lived longer (mean=30 days) than nonsurviving CON infants (mean=5 days). Complications were equally frequent in both group except that hyperglycemia occurred more often in infants receiving INS. The plasma aminogram of the LBW infant is described and compared to those of the full-term infant and adult. Hypoaminoacidemia was present at birth in the LBW infants, concentrations of glutamine, alanine, glycine, histidine, and ornithine being significantly (P<0.05) below FT values. During INS, elevations of threonine, serine, and methionine above FT values occurred. Glutamine remained subnormal despite INS. Recommendations for an INS solution more suitable for use in LBW infants are presented.
AB - In 42 low-birth-weight infants (<1,200 gm), we have compared the effects of intravenous nutrition supplement versus conventional feedings on growth, morbidity, mortality, and plasma amino acid patterns. Despite similar total caloric intake in INS and control groups, weight gain was greater in the INS infants. The overall mortality rate did not differ in the two groups. Nonsurviving infants receiving INS lived longer (mean=30 days) than nonsurviving CON infants (mean=5 days). Complications were equally frequent in both group except that hyperglycemia occurred more often in infants receiving INS. The plasma aminogram of the LBW infant is described and compared to those of the full-term infant and adult. Hypoaminoacidemia was present at birth in the LBW infants, concentrations of glutamine, alanine, glycine, histidine, and ornithine being significantly (P<0.05) below FT values. During INS, elevations of threonine, serine, and methionine above FT values occurred. Glutamine remained subnormal despite INS. Recommendations for an INS solution more suitable for use in LBW infants are presented.
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U2 - 10.1016/S0022-3476(75)80369-6
DO - 10.1016/S0022-3476(75)80369-6
M3 - Article
VL - 86
SP - 766
EP - 772
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 5
ER -