Abstract
Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.
| Original language | English |
|---|---|
| Pages (from-to) | 333-336 |
| Number of pages | 4 |
| Journal | International Journal of Gynecological Cancer |
| Volume | 6 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 1996 |
| Externally published | Yes |
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Keywords
- placental site tumor
- trophoblastic disease
ASJC Scopus subject areas
- Cancer Research
- Obstetrics and Gynecology
- Oncology
Cite this
Placental site trophoblastic tumor presenting with scalp metastases. / Hartenbach, E. M.; Saltzman, A. K.; Zachary, C. B.; Osborne, J. L.; Okagaki, T.; Twiggs, L. B.
In: International Journal of Gynecological Cancer, Vol. 6, No. 4, 01.01.1996, p. 333-336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Placental site trophoblastic tumor presenting with scalp metastases
AU - Hartenbach, E. M.
AU - Saltzman, A. K.
AU - Zachary, C. B.
AU - Osborne, J. L.
AU - Okagaki, T.
AU - Twiggs, L. B.
PY - 1996/1/1
Y1 - 1996/1/1
N2 - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.
AB - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.
KW - placental site tumor
KW - trophoblastic disease
UR - http://www.scopus.com/inward/record.url?scp=0030035212&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030035212&partnerID=8YFLogxK
U2 - 10.1046/j.1525-1438.1996.06040333.x
DO - 10.1046/j.1525-1438.1996.06040333.x
M3 - Article
AN - SCOPUS:0030035212
VL - 6
SP - 333
EP - 336
JO - International Journal of Gynecological Cancer
JF - International Journal of Gynecological Cancer
SN - 1048-891X
IS - 4
ER -