Placental site trophoblastic tumor presenting with scalp metastases

E. M. Hartenbach, A. K. Saltzman, C. B. Zachary, J. L. Osborne, T. Okagaki, L. B. Twiggs

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalInternational Journal of Gynecological Cancer
Volume6
Issue number4
DOIs
StatePublished - Jan 1 1996
Externally publishedYes

Fingerprint

Placental Site Trophoblastic Tumor
Scalp
Neoplasm Metastasis
Uterus
Gestational Trophoblastic Disease
Skin
Uterine Hemorrhage
Amenorrhea
Dactinomycin
Vincristine
Etoposide
Methotrexate
Cyclophosphamide
Drug Therapy

Keywords

  • placental site tumor
  • trophoblastic disease

ASJC Scopus subject areas

  • Cancer Research
  • Obstetrics and Gynecology
  • Oncology

Cite this

Hartenbach, E. M., Saltzman, A. K., Zachary, C. B., Osborne, J. L., Okagaki, T., & Twiggs, L. B. (1996). Placental site trophoblastic tumor presenting with scalp metastases. International Journal of Gynecological Cancer, 6(4), 333-336. https://doi.org/10.1046/j.1525-1438.1996.06040333.x

Placental site trophoblastic tumor presenting with scalp metastases. / Hartenbach, E. M.; Saltzman, A. K.; Zachary, C. B.; Osborne, J. L.; Okagaki, T.; Twiggs, L. B.

In: International Journal of Gynecological Cancer, Vol. 6, No. 4, 01.01.1996, p. 333-336.

Research output: Contribution to journalArticle

Hartenbach, EM, Saltzman, AK, Zachary, CB, Osborne, JL, Okagaki, T & Twiggs, LB 1996, 'Placental site trophoblastic tumor presenting with scalp metastases', International Journal of Gynecological Cancer, vol. 6, no. 4, pp. 333-336. https://doi.org/10.1046/j.1525-1438.1996.06040333.x
Hartenbach, E. M. ; Saltzman, A. K. ; Zachary, C. B. ; Osborne, J. L. ; Okagaki, T. ; Twiggs, L. B. / Placental site trophoblastic tumor presenting with scalp metastases. In: International Journal of Gynecological Cancer. 1996 ; Vol. 6, No. 4. pp. 333-336.
@article{ddf9b82a9795464f8f29343d94583542,
title = "Placental site trophoblastic tumor presenting with scalp metastases",
abstract = "Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.",
keywords = "placental site tumor, trophoblastic disease",
author = "Hartenbach, {E. M.} and Saltzman, {A. K.} and Zachary, {C. B.} and Osborne, {J. L.} and T. Okagaki and Twiggs, {L. B.}",
year = "1996",
month = "1",
day = "1",
doi = "10.1046/j.1525-1438.1996.06040333.x",
language = "English",
volume = "6",
pages = "333--336",
journal = "International Journal of Gynecological Cancer",
issn = "1048-891X",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Placental site trophoblastic tumor presenting with scalp metastases

AU - Hartenbach, E. M.

AU - Saltzman, A. K.

AU - Zachary, C. B.

AU - Osborne, J. L.

AU - Okagaki, T.

AU - Twiggs, L. B.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

AB - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

KW - placental site tumor

KW - trophoblastic disease

UR - http://www.scopus.com/inward/record.url?scp=0030035212&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030035212&partnerID=8YFLogxK

U2 - 10.1046/j.1525-1438.1996.06040333.x

DO - 10.1046/j.1525-1438.1996.06040333.x

M3 - Article

AN - SCOPUS:0030035212

VL - 6

SP - 333

EP - 336

JO - International Journal of Gynecological Cancer

JF - International Journal of Gynecological Cancer

SN - 1048-891X

IS - 4

ER -