Placental site trophoblastic tumor presenting with scalp metastases

E. M. Hartenbach; A. K. Saltzman; C. B. Zachary; J. L. Osborne; T. Okagaki; L. B. Twiggs

doi:10.1046/j.1525-1438.1996.06040333.x

Placental site trophoblastic tumor presenting with scalp metastases

E. M. Hartenbach, A. K. Saltzman, C. B. Zachary, J. L. Osborne, T. Okagaki, L. B. Twiggs

Obstetrics & Gynecology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

Original language	English (US)
Pages (from-to)	333-336
Number of pages	4
Journal	International Journal of Gynecological Cancer
Volume	6
Issue number	4
DOIs	https://doi.org/10.1046/j.1525-1438.1996.06040333.x
State	Published - Jan 1 1996

Keywords

placental site tumor
trophoblastic disease

ASJC Scopus subject areas

Cancer Research
Obstetrics and Gynecology
Oncology

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title = "Placental site trophoblastic tumor presenting with scalp metastases",

abstract = "Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.",

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author = "Hartenbach, {E. M.} and Saltzman, {A. K.} and Zachary, {C. B.} and Osborne, {J. L.} and T. Okagaki and Twiggs, {L. B.}",

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AU - Hartenbach, E. M.

AU - Saltzman, A. K.

AU - Zachary, C. B.

AU - Osborne, J. L.

AU - Okagaki, T.

AU - Twiggs, L. B.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

AB - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

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Placental site trophoblastic tumor presenting with scalp metastases

Abstract

Keywords

ASJC Scopus subject areas

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