Placental site trophoblastic tumor presenting with scalp metastases

E. M. Hartenbach, A. K. Saltzman, C. B. Zachary, J. L. Osborne, T. Okagaki, L. B. Twiggs

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.

Original languageEnglish (US)
Pages (from-to)333-336
Number of pages4
JournalInternational Journal of Gynecological Cancer
Issue number4
StatePublished - Jan 1 1996


  • placental site tumor
  • trophoblastic disease

ASJC Scopus subject areas

  • Cancer Research
  • Obstetrics and Gynecology
  • Oncology


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