Abstract
Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate- actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner.
Original language | English (US) |
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Pages (from-to) | 333-336 |
Number of pages | 4 |
Journal | International Journal of Gynecological Cancer |
Volume | 6 |
Issue number | 4 |
DOIs | |
State | Published - Jan 1 1996 |
Keywords
- placental site tumor
- trophoblastic disease
ASJC Scopus subject areas
- Cancer Research
- Obstetrics and Gynecology
- Oncology