Placebo-controlled study of pramiracetam in Young males with memory and cognitive problems resulting from head injury and anoxia

Alvin Mclean, Diana D. Cardenas, Donna Burgess, Elkan Gamzu

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The current study evaluated under double-blind placebo-controlled conditions, the safety and efficacy of 400 mg pramiracetam sulphate TID in treating memory and other cognitive problems of males who have sustained brain injuries. The results of the study indicate that subject performance in measures of memory, especially delayed recall, evidenced clinically significant improvements after the administration of pramiracetam sulphate as compared to placebo. This improvement was maintained during an 18-month open-trial period on the medication as well as during a 1-month follow-up period after the pramiracetam was discontinued.

Original languageEnglish (US)
Pages (from-to)375-380
Number of pages6
JournalBrain Injury
Volume5
Issue number4
DOIs
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Developmental and Educational Psychology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Placebo-controlled study of pramiracetam in Young males with memory and cognitive problems resulting from head injury and anoxia'. Together they form a unique fingerprint.

  • Cite this