Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion

Arturo Zárate; Elías S. Canales; Jorge Soria; Carlos MacGregor; Pedro J. Maneiro; Andrew V. Schally

doi:10.1016/0002-9378(73)90947-2

Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion

Arturo Zárate, Elías S. Canales, Jorge Soria, Carlos MacGregor, Pedro J. Maneiro, Andrew V. Schally

Pathology

Research output: Contribution to journal › Article

20 Scopus citations

Abstract

Thirteen pregnant women were given synthetic luteinizing hormone-releasing hormone (LH-RH) by a single intravenous injection. Serum concentrations of follicle-stimulating hormone (FSH) were measured by radioimmunoassay. A significant rise in FSH was found after LH-RH administration in 10 of the 13 patients; however the response was very variable in each case. The maximum increase in the serum levels of FSH above the base line remained constant with the advancement of pregnancy. The present study confirms that the pituitary gland responds to LH-RH administration with the secretion of FSH despite the high levels of sex steroid and chorionic gonadotropin during pregnancy.

Original language	English (US)
Pages (from-to)	1121-1123
Number of pages	3
Journal	American journal of obstetrics and gynecology
Volume	116
Issue number	8
DOIs	https://doi.org/10.1016/0002-9378(73)90947-2
State	Published - Aug 15 1973

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ASJC Scopus subject areas

Obstetrics and Gynecology

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Zárate, A., Canales, E. S., Soria, J., MacGregor, C., Maneiro, P. J., & Schally, A. V. (1973). Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion. American journal of obstetrics and gynecology, 116(8), 1121-1123. https://doi.org/10.1016/0002-9378(73)90947-2

Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy : Effect on follicle-stimulating hormone secretion. / Zárate, Arturo; Canales, Elías S.; Soria, Jorge; MacGregor, Carlos; Maneiro, Pedro J.; Schally, Andrew V.

In: American journal of obstetrics and gynecology, Vol. 116, No. 8, 15.08.1973, p. 1121-1123.

Research output: Contribution to journal › Article

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10.1016/0002-9378(73)90947-2