Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion

Arturo Zárate; Elías S. Canales; Jorge Soria; Carlos MacGregor; Pedro J. Maneiro; Andrew V. Schally

doi:10.1016/0002-9378(73)90947-2

Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion

Arturo Zárate, Elías S. Canales, Jorge Soria, Carlos MacGregor, Pedro J. Maneiro, Andrew V. Schally

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Thirteen pregnant women were given synthetic luteinizing hormone-releasing hormone (LH-RH) by a single intravenous injection. Serum concentrations of follicle-stimulating hormone (FSH) were measured by radioimmunoassay. A significant rise in FSH was found after LH-RH administration in 10 of the 13 patients; however the response was very variable in each case. The maximum increase in the serum levels of FSH above the base line remained constant with the advancement of pregnancy. The present study confirms that the pituitary gland responds to LH-RH administration with the secretion of FSH despite the high levels of sex steroid and chorionic gonadotropin during pregnancy.

Original language	English (US)
Pages (from-to)	1121-1123
Number of pages	3
Journal	American journal of obstetrics and gynecology
Volume	116
Issue number	8
DOIs	https://doi.org/10.1016/0002-9378(73)90947-2
State	Published - Aug 15 1973
Externally published	Yes

ASJC Scopus subject areas

Obstetrics and Gynecology

Access to Document

10.1016/0002-9378(73)90947-2

Cite this

Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy : Effect on follicle-stimulating hormone secretion. / Zárate, Arturo; Canales, Elías S.; Soria, Jorge; MacGregor, Carlos; Maneiro, Pedro J.; Schally, Andrew V.

In: American journal of obstetrics and gynecology, Vol. 116, No. 8, 15.08.1973, p. 1121-1123.

Research output: Contribution to journal › Article › peer-review

@article{109bf8bd3c7f4edd8d2023ed02c2c04f,

title = "Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion",

abstract = "Thirteen pregnant women were given synthetic luteinizing hormone-releasing hormone (LH-RH) by a single intravenous injection. Serum concentrations of follicle-stimulating hormone (FSH) were measured by radioimmunoassay. A significant rise in FSH was found after LH-RH administration in 10 of the 13 patients; however the response was very variable in each case. The maximum increase in the serum levels of FSH above the base line remained constant with the advancement of pregnancy. The present study confirms that the pituitary gland responds to LH-RH administration with the secretion of FSH despite the high levels of sex steroid and chorionic gonadotropin during pregnancy.",

author = "Arturo Z{\'a}rate and Canales, {El{\'i}as S.} and Jorge Soria and Carlos MacGregor and Maneiro, {Pedro J.} and Schally, {Andrew V.}",

year = "1973",

month = aug,

day = "15",

doi = "10.1016/0002-9378(73)90947-2",

language = "English (US)",

volume = "116",

pages = "1121--1123",

journal = "American Journal of Obstetrics and Gynecology",

issn = "0002-9378",

publisher = "Mosby Inc.",

number = "8",

}

TY - JOUR

T1 - Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy

T2 - Effect on follicle-stimulating hormone secretion

AU - Zárate, Arturo

AU - Canales, Elías S.

AU - Soria, Jorge

AU - MacGregor, Carlos

AU - Maneiro, Pedro J.

AU - Schally, Andrew V.

PY - 1973/8/15

Y1 - 1973/8/15

N2 - Thirteen pregnant women were given synthetic luteinizing hormone-releasing hormone (LH-RH) by a single intravenous injection. Serum concentrations of follicle-stimulating hormone (FSH) were measured by radioimmunoassay. A significant rise in FSH was found after LH-RH administration in 10 of the 13 patients; however the response was very variable in each case. The maximum increase in the serum levels of FSH above the base line remained constant with the advancement of pregnancy. The present study confirms that the pituitary gland responds to LH-RH administration with the secretion of FSH despite the high levels of sex steroid and chorionic gonadotropin during pregnancy.

AB - Thirteen pregnant women were given synthetic luteinizing hormone-releasing hormone (LH-RH) by a single intravenous injection. Serum concentrations of follicle-stimulating hormone (FSH) were measured by radioimmunoassay. A significant rise in FSH was found after LH-RH administration in 10 of the 13 patients; however the response was very variable in each case. The maximum increase in the serum levels of FSH above the base line remained constant with the advancement of pregnancy. The present study confirms that the pituitary gland responds to LH-RH administration with the secretion of FSH despite the high levels of sex steroid and chorionic gonadotropin during pregnancy.

UR - http://www.scopus.com/inward/record.url?scp=0015788568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015788568&partnerID=8YFLogxK

U2 - 10.1016/0002-9378(73)90947-2

DO - 10.1016/0002-9378(73)90947-2

M3 - Article

C2 - 4578635

AN - SCOPUS:0015788568

VL - 116

SP - 1121

EP - 1123

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 8

ER -

Pituitary responsiveness to synthetic luteinizing hormone-releasing hormone during pregnancy: Effect on follicle-stimulating hormone secretion

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this