Pituitary response to luteinizing hormone releasing hormone after induced abortion in the first and second trimesters

M. E. Domenzain, A. G. Shapiro, A. A. Bezjian, W. J. LeMaire

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Abstract

Luteinizing hormone-releasing hormone (LHRH) (100 μg) was administered subcutaneously to healthy female volunteers 2 and 4 weeks after induced abortion in the first trimester (group A) and the midtrimester (group B). Four patients were studied in each group. The response to LHRH was determined in terms of plasma LH and follicle-stimulating hormone levels. Adequate pituitary response occurred in subjects of group A at both 2 and 4 weeks. In group B pituitary unresponsiveness was found at 2 weeks which persisted to some extent at 4 weeks. These data are in accord with the pituitary unresponsiveness observed after termination of pregnancy at term and suggest that the duration of pregnancy has an influence on the development of this unresponsiveness.

Original languageEnglish (US)
Pages (from-to)531-534
Number of pages4
JournalFertility and Sterility
Volume28
Issue number5
StatePublished - Jan 1 1977

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ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Domenzain, M. E., Shapiro, A. G., Bezjian, A. A., & LeMaire, W. J. (1977). Pituitary response to luteinizing hormone releasing hormone after induced abortion in the first and second trimesters. Fertility and Sterility, 28(5), 531-534.