TY - JOUR
T1 - Pituitary adenoma, menstrual disturbance, hirsutism, and abnormal glucose tolerance
AU - Shapiro, A. G.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - The association of chronic anovulation and hirsutism with a pituitary adenoma and hyperprolactinemia has been described previously. The association of hirsutism, an abnormal glucose tolerance test, and hyperinsulinism has also been reported previously. Two patients are now presented with an unusual association of pituitary microadenoma, oligomenorrhea/amenorrhea, hirsutism, and an abnormal glucose tolerance test. In addition, the surprise finding about these two cases is that, following the surgical removal of the pituitary microadenoma, not only did menses resume and the prolactin level decline, but the testosterone level fell to normal female ranges, hair growth decreased, and glucose tolerance improved.
AB - The association of chronic anovulation and hirsutism with a pituitary adenoma and hyperprolactinemia has been described previously. The association of hirsutism, an abnormal glucose tolerance test, and hyperinsulinism has also been reported previously. Two patients are now presented with an unusual association of pituitary microadenoma, oligomenorrhea/amenorrhea, hirsutism, and an abnormal glucose tolerance test. In addition, the surprise finding about these two cases is that, following the surgical removal of the pituitary microadenoma, not only did menses resume and the prolactin level decline, but the testosterone level fell to normal female ranges, hair growth decreased, and glucose tolerance improved.
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U2 - 10.1016/S0015-0282(16)45328-8
DO - 10.1016/S0015-0282(16)45328-8
M3 - Article
C2 - 7202748
AN - SCOPUS:0019863236
VL - 35
SP - 226
EP - 229
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 2
ER -