Pigmentary deposition disorders

Jessica Linder, Maria Miteva, Paolo Romanelli

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Pigmentary deposition skin disorders are characterized by abnormal accumulation of pigmented substances that are of endogenous or exogenous derivation. Endogenous pigmentary deposition disorders are due to inherited diseases, mainly alkaptonuria (ochronosis). Exogenous pigmentary deposition disorders are due to drugs including antimalarials, phenothiazines, tetracyclines, amiodarone, clofazimine, chemotherapeutic agents, and hydroquinone (exogenous ochronosis) or heavy metals including silver, gold, mercury, arsenic, bismuth, and lead. Hyperpigmentation due to drugs is usually reversible with discontinuation of the therapy.

Original languageEnglish (US)
Title of host publicationClinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease
PublisherSpringer New York
Number of pages10
ISBN (Print)9781607611806
StatePublished - Dec 1 2010


  • Alkaptonuria
  • Drugs
  • Endogenous pigmentation
  • Exoge-nous pigmentation
  • Heavy metals

ASJC Scopus subject areas

  • Medicine(all)


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