Abstract
The physiological responses of juvenile rainbow trout (Oncorhynchus mykiss) to lithium (as LiCl) in moderately hard freshwater (CaCO3 = 120-140 ppm, Na+ = ∼0.6 mM) were studied. The study employed a 15-day step-up exposure regime; 66 μg/L Li for the first 9 days and 528 μg/L for the next 6 days. The concentrations of plasma ions, apolipoprotein AI, total cholesterol, and fatty acids, as well as metabolic enzyme citrate synthase (CS) and Na+,K+-ATPase activities in the gill were measured. Li affected fish by exacerbated diffusive Na+ losses at the gills in the beginning of exposure and a decrease of branchial CS activity. Detrimental effects were shown in fish exposed to 528 μg Li/L. These included a reduction of gill Na+,K+-ATPase activity, possibly related to observed lower concentrations of free fatty acids and cholesterol in gill tissue.
Original language | English (US) |
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Pages (from-to) | 632-638 |
Number of pages | 7 |
Journal | Archives of environmental contamination and toxicology |
Volume | 53 |
Issue number | 4 |
DOIs | |
State | Published - Nov 1 2007 |
Keywords
- Apolipoprotein AI
- Enzyme activity
- Fish gill
- Lipids
- Lithium
- Plasma ions
ASJC Scopus subject areas
- Environmental Science(all)
- Environmental Chemistry
- Toxicology