Fototerapia en el tratamiento de la micosis fungoide

Translated title of the contribution: Phototherapy for the treatment of mycosis fungoides

Claudia Juliana Mariaca-Flórez, A. M. Londono-Garcia, O. J. Valencia-Ocampo, N. Jaimes, M. M. Velásquez-Lopera

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Phototherapy is the first-line treatment for early stage mycosis fungoides (MF). However, there is lack of evidence-based recommendations. This article reviews the literature related to the use of phototherapy in the treatment of MF. A systematic review of the literature was performed. MEDLINE database was used to search for articles published between January 1976 and December 2013. The collected information was analyzed and the quality of the studies was assessed using Jadad scale for randomized clinical trials, and CASPE for cohort, case and controls and qualitative studies. Clinical recommendations were given based on the level of evidence following the AGREE II technique (Appraisal of Guidelines for Research & Evaluation II). A total of 50 articles met the inclusion criteria. For early stages (IA, IB and IIA), oral PUVA, NB-UVB and UVA-1 had the greatest level of evidence, with a level of evidence and grade of recommendation of11-3, B, lll-B y III-B, respectively. Phototherapy is the first-line treatment for early stage MF. Oral PUVA showed the highest level of evidence, followed by NB-UVB and UVA-1. The implementation of these recommendations may permit the unification of concepts and schemes in the treatment of MF with phototherapy.

Translated title of the contributionPhototherapy for the treatment of mycosis fungoides
Original languageSpanish
Pages (from-to)115-136
Number of pages22
JournalDermatologia Revista Mexicana
Volume61
Issue number2
StatePublished - Mar 1 2017
Externally publishedYes

Keywords

  • Cutaneous T cell lymphoma
  • Mycosis fungoides
  • Photochemotherapy
  • Phototherapy

ASJC Scopus subject areas

  • Dermatology

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