Photodynamic therapy for choroidal metastasis from carcinoid tumor

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50%. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.

Original languageEnglish
Pages (from-to)1143-1145
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume137
Issue number6
DOIs
StatePublished - Jun 1 2004
Externally publishedYes

Fingerprint

Carcinoid Tumor
Photochemotherapy
Neoplasm Metastasis
Visual Acuity
Radiotherapy
Drug Therapy
Retinal Detachment
Tumor Burden
Neoplasms
Therapeutics
Biopsy
Light
Lung
verteporfin

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Photodynamic therapy for choroidal metastasis from carcinoid tumor. / William Harbour, J.

In: American Journal of Ophthalmology, Vol. 137, No. 6, 01.06.2004, p. 1143-1145.

Research output: Contribution to journalArticle

@article{ad668e85b17a41e89662e1a3b6fd7e53,
title = "Photodynamic therapy for choroidal metastasis from carcinoid tumor",
abstract = "Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50{\%}. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.",
author = "{William Harbour}, J.",
year = "2004",
month = "6",
day = "1",
doi = "10.1016/j.ajo.2004.01.009",
language = "English",
volume = "137",
pages = "1143--1145",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "6",

}

TY - JOUR

T1 - Photodynamic therapy for choroidal metastasis from carcinoid tumor

AU - William Harbour, J.

PY - 2004/6/1

Y1 - 2004/6/1

N2 - Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50%. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.

AB - Purpose To determine the efficacy of photodynamic therapy for the treatment of a choroidal metastasis unresponsive to chemotherapy and radiation therapy. Design Interventional case report. Methods Photodynamic therapy with verteporfin was performed. Visual acuity, local tumor control, and complications were assessed. Results A 72-year-old woman was diagnosed with bilateral, biopsy-proven choroidal metastasis from a pulmonary carcinoid tumor that was resistant to chemotherapy and radiotherapy. The tumor in the left eye caused a retinal detachment and vision loss to light perception. The smaller lesion in the right eye progressively enlarged toward the fovea despite therapy and was treated with photodynamic therapy with verteporfin. Within 2 months, the exudative detachment resolved, the visual acuity returned to baseline, and the tumor volume decreased by 50%. Conclusion Photodynamic therapy may be an effective treatment option for selected patients with choroidal metastasis.

UR - http://www.scopus.com/inward/record.url?scp=2942616674&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2942616674&partnerID=8YFLogxK

U2 - 10.1016/j.ajo.2004.01.009

DO - 10.1016/j.ajo.2004.01.009

M3 - Article

C2 - 15183811

AN - SCOPUS:2942616674

VL - 137

SP - 1143

EP - 1145

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 6

ER -