Abstract
Photodynamic therapy (PDT) refers to the therapeutic use of a locally concentrated photosensitizing agent and subsequent light irradiation to produce reactive oxygen intermediates, specifically singlet oxygen species. The accumulation of the light-induced singlet oxygen in the target tissue causes selective damage to biologically important structures. PDT has an extensive history of use in oncology and has recently gained popularity in the management of dermatologic conditions, both malignant and benign. PDT has quickly become an attractive option for the non-invasive treatment of a variety of dermatologic indications due to a low incidence of adverse events and excellent cosmetic outcomes, even when treating large and/or multiple lesions. This chapter will discuss the currently supported indications as well as any known contraindications to PDT use in dermatology. Procedural techniques and pre- and post-operative considerations will also be addressed along with prevention and management of complications associated with the use of PDT.
| Original language | English (US) |
|---|---|
| Title of host publication | Handbook of Lasers in Dermatology |
| Publisher | Springer London |
| Pages | 279-291 |
| Number of pages | 13 |
| ISBN (Electronic) | 9781447153221 |
| ISBN (Print) | 9781447153214 |
| DOIs | |
| State | Published - Jan 1 2014 |
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Keywords
- Actinic keratosis
- Aminolevulinic acid
- Dermatology
- Laser
- Light
- Photodynamic therapy
- Photosensitizer
- Skin cancer
- Treatment
ASJC Scopus subject areas
- Medicine(all)
Cite this
Photodynamic therapy. / Savas, Jessica A.; Ledon, Jennifer A.; França, Kaitlein; Nouri, Keyvan.
Handbook of Lasers in Dermatology. Springer London, 2014. p. 279-291.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Photodynamic therapy
AU - Savas, Jessica A.
AU - Ledon, Jennifer A.
AU - França, Kaitlein
AU - Nouri, Keyvan
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Photodynamic therapy (PDT) refers to the therapeutic use of a locally concentrated photosensitizing agent and subsequent light irradiation to produce reactive oxygen intermediates, specifically singlet oxygen species. The accumulation of the light-induced singlet oxygen in the target tissue causes selective damage to biologically important structures. PDT has an extensive history of use in oncology and has recently gained popularity in the management of dermatologic conditions, both malignant and benign. PDT has quickly become an attractive option for the non-invasive treatment of a variety of dermatologic indications due to a low incidence of adverse events and excellent cosmetic outcomes, even when treating large and/or multiple lesions. This chapter will discuss the currently supported indications as well as any known contraindications to PDT use in dermatology. Procedural techniques and pre- and post-operative considerations will also be addressed along with prevention and management of complications associated with the use of PDT.
AB - Photodynamic therapy (PDT) refers to the therapeutic use of a locally concentrated photosensitizing agent and subsequent light irradiation to produce reactive oxygen intermediates, specifically singlet oxygen species. The accumulation of the light-induced singlet oxygen in the target tissue causes selective damage to biologically important structures. PDT has an extensive history of use in oncology and has recently gained popularity in the management of dermatologic conditions, both malignant and benign. PDT has quickly become an attractive option for the non-invasive treatment of a variety of dermatologic indications due to a low incidence of adverse events and excellent cosmetic outcomes, even when treating large and/or multiple lesions. This chapter will discuss the currently supported indications as well as any known contraindications to PDT use in dermatology. Procedural techniques and pre- and post-operative considerations will also be addressed along with prevention and management of complications associated with the use of PDT.
KW - Actinic keratosis
KW - Aminolevulinic acid
KW - Dermatology
KW - Laser
KW - Light
KW - Photodynamic therapy
KW - Photosensitizer
KW - Skin cancer
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=85028374086&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028374086&partnerID=8YFLogxK
U2 - 10.1007/978-1-4471-5322-1_18
DO - 10.1007/978-1-4471-5322-1_18
M3 - Chapter
SN - 9781447153214
SP - 279
EP - 291
BT - Handbook of Lasers in Dermatology
PB - Springer London
ER -