Major depression is a psychiatric disorder associated with significant morbidity, lost productivity, and high health care utilization costs. Its pharmacologic treatment has changed during the past decade due to the development of new agents. While the newer antidepressants do not appear to offer greater efficacy over the older antidepressants, they are associated with fewer side effects and have fewer dietary and medical prescribing restrictions and contraindications. This article reviews the formulary considerations-efficacy and side effect profiles, pharmacoeconomic considerations, dosing and administration-for each pharmacologic option available to treat depression.
|Original language||English (US)|
|State||Published - Feb 1 1997|
ASJC Scopus subject areas
- Pharmacology (medical)