Pharmacological Treatment of Alcohol Abuse/Dependence with Psychiatric Comorbidity

Charlene E. Le Fauve, Raye Z. Litten, Carrie L. Randall, Darlene H. Moak, Ihsan M Salloum, Alan I. Green

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

This article represents the proceedings of a symposium at the 2003 annual meeting RSA in Fort Lauderdale, FL. It was organized and cochaired by Charlene E. Le Fauve and Carrie L. Randall. The presentations were (1) Introduction, by Charlene E. Le Fauve and Raye Z. Litten; (2) Treatment of co-occurring alcohol use and anxiety disorders, by Carrie L. Randall and Sarah W. Book; (3) Pharmacological treatment of alcohol dependent patients with comorbid depression, by Darlene H. Moak; (4) Efficacy of valproate in bipolar alcoholics: a double blind, placebo-controlled study, by Ihsan M. Salloum, Jack R. Cornelius, Dennis C. Daley, Levent Kirisci, Johnathan Himmelhoch, and Michael E. Thase; (5) Alcoholism and schizophrenia: effects of antipsychotics, by Alan I. Green, Robert E. Drake, Suzannah V. Zimmet, Rael D. Strous, Melinda Salomon, and Mark Brenner; and (6) Conclusions, by Charlene E. Le Fauve; discussant, Raye Z. Litten. Alcohol-dependent individuals have exceptionally high rates of co-occurring psychiatric disorders. Although this population is more likely to seek alcoholism treatment than noncomorbid alcoholics, the prognosis for treatment is often poor, particularly among patients with more severe psychiatric illnesses. Development of effective interventions to treat this population is in the early stages of research. Although the interaction between the psychiatric condition and alcoholism is complex, progress has been made. The NIAAA has supported a number of state-of-the-art pharmacological and behavioral trials in a variety of comorbid psychiatric disorders. Some of these trials have been completed and are presented here. The symposium presented some new research findings from clinical studies with the aim of facilitating the development of treatments that improve alcohol and psychiatric outcomes among individuals with alcohol-use disorders and co-occurring psychiatric disorders. The panel focused on social anxiety disorder, depression, bipolar disorder, and schizophrenia.

Original languageEnglish
Pages (from-to)302-312
Number of pages11
JournalAlcoholism: Clinical and Experimental Research
Volume28
Issue number2
DOIs
StatePublished - Feb 1 2004
Externally publishedYes

Fingerprint

Alcoholism
Psychiatry
Comorbidity
Alcohols
Pharmacology
Alcoholics
Schizophrenia
National Institute on Alcohol Abuse and Alcoholism (U.S.)
Therapeutics
Depression
Jacks
Valproic Acid
Anxiety Disorders
Bipolar Disorder
Research
Antipsychotic Agents
Population
Placebos

Keywords

  • Alcoholism Treatment
  • Pharmacotherapy
  • Psychiatric Comorbidity

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology

Cite this

Pharmacological Treatment of Alcohol Abuse/Dependence with Psychiatric Comorbidity. / Le Fauve, Charlene E.; Litten, Raye Z.; Randall, Carrie L.; Moak, Darlene H.; Salloum, Ihsan M; Green, Alan I.

In: Alcoholism: Clinical and Experimental Research, Vol. 28, No. 2, 01.02.2004, p. 302-312.

Research output: Contribution to journalArticle

Le Fauve, Charlene E. ; Litten, Raye Z. ; Randall, Carrie L. ; Moak, Darlene H. ; Salloum, Ihsan M ; Green, Alan I. / Pharmacological Treatment of Alcohol Abuse/Dependence with Psychiatric Comorbidity. In: Alcoholism: Clinical and Experimental Research. 2004 ; Vol. 28, No. 2. pp. 302-312.
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