Pharmacological treatment occult gastrointestinal bleeding

Gastrointestinal bleeding can be defined as obscure when the source of acute or chronic blood loss has not been identified after esophagogastroduodenoscopy, colonoscopy, and radiological studies of the small bowel, Either intermittent or continuous, the bleeding may range from microscopic oozing manifested by hemoccult-positive stools and iron deficiency anemia to recurrent melena or hematochezia. The majority of patients will respond to iron replacement, but a small subset will require multiple blood transfusions. Pharmacological treatment is available for well-selected patients.