Pharmacologic approaches to management of arrhythmias in patients with cardiomyopathy and heart failure

Robert J. Myerburg, Kenneth M. Kessler, Liaqat Zaman, Pedro Fernandez, Eduardo DeMarchena, Agustin Castellanos

Research output: Contribution to journalArticle

10 Scopus citations


Interactions between disordered cardiac rhythm and abnormal cardiac hemodynamic function are well recognized. Demonatrations of this relationship include the relationship between prognostic significance of ventricular ectopy and left ventricular ejection fraction, impairment of ventricular function in association with loss of atrial systole in disease states, increased risk of potentially lethal arrhythmias in the myopathic ventricle, and the evolution of advanced grades of ventricular arrhythmias in acute heart failure. With the development of newer and more potent antiarrhythmic agents, in conjunction with drugs that can improve the failing circulation, it is now possible to clarify these interrelationships and perhaps develop new strafegies for clinical management.

Original languageEnglish (US)
Pages (from-to)1273-1279
Number of pages7
JournalAmerican Heart Journal
Issue number5
StatePublished - Nov 1987


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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