Peyronie's disease in a patient after COVID-19 infection: A case report

Quinn Rainer, Manuel Molina, Emad Ibrahim, Russell Saltzman, Thomas Masterson, Ranjith Ramasamy

Research output: Contribution to journalArticlepeer-review


Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV-2), which demonstrates the ability to invade endothelial cells and cause systemic inflammation. Many possible long-term sequelae of COVID-19 remain unidentified. We describe a case of a man who developed Peyronie's disease after a resolved COVID-19 infection. Erectile dysfunction was confirmed by the International Index of Erectile Function-15(IIEF) and Sexual Health Inventory for Men(SHIM) scores. A diagnosis was Peyronie's disease was confirmed on ultrasound. Furthermore, he was found to have low endothelial progenitor cells colony-forming units and low brachial artery flow-mediated vasodilation, both of that are indicative of endothelial dysfunction. This case suggests Peyronie's disease should be considered as a possible sequela of COVID-19 infection and providers should inquire about a history of COVID-19 infection in patients presenting with Peyronie's disease.

Original languageEnglish (US)
Article numbere14219
Issue number11
StatePublished - Dec 2021


  • COVID-19
  • Peyronie's disease
  • coronavirus
  • endothelial dysfunction
  • erectile dysfunction

ASJC Scopus subject areas

  • Endocrinology
  • Urology


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