Perverted head-shaking nystagmus: A possible mechanism

Alireza Minagar, William A. Sheremata, Ronald J. Tusa

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


The authors describe a patient with acute MS who developed vertigo (tumbling) and downbeat nystagmus upon horizontal head oscillation (perverted head-shaking nystagmus). The only abnormality on brain MRI was a hyperintense signal in the caudal medulla that contains the nucleus Roller and nucleus intercalatus. These nuclei project to structures involved in the velocity storage system for horizontal vestibulocular reflex (VOR) and vertical VOR, and also to the vestibular cerebellum. The authors offer possible mechanisms for perverted nystagmus in this patient.

Original languageEnglish (US)
Pages (from-to)887-889
Number of pages3
Issue number5
StatePublished - Sep 11 2001

ASJC Scopus subject areas

  • Clinical Neurology


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